Results 101 to 110 of about 1,086,391 (237)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

#Nicotineaddiction on TikTok: A quantitative content analysis of top-viewed posts. [PDF]

open access: yesTob Induc Dis, 2022
Marynak KL   +4 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Analyzing first-semester chemistry students’ transactive talk and problem-solving activities in an intervention study through a quantitative coding manual

open access: yesFrontiers in Education
IntroductionDuring the COVID-19 pandemic, digital video conferencing formats temporarily became the new norm at universities. Due to social distancing, these environments were often the only way for students to work together.
David Johannes Hauck   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Türkiye’de Lisansüstü Halkla İlişkiler Eğitimi Üzerine Bir Araştırma: Doktora Tezlerinin Halkla İlişkiler Alanına Katkısının Niceliksel İçerik Analizi 2008-2017

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2018
Türkiye’de halkla ilişkiler alanındaki bilgi birikiminin özellikle son yirmi yılda büyük bir gelişim kaydettiği ve halkla ilişkiler mesleğinin gerek özel sektör gerek kamu kuruluşları gerekse kar amacı gütmeyen kurum ve kuruluşlarda güçlü bir yönetim ...
Başak Solmaz, Yunus Ergen, Öznur Alkan
doaj  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

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