Results 121 to 130 of about 1,263,541 (299)

Airline key change drivers and business environmental analysis in the Southeast Asia: strategic planning perspectives [PDF]

open access: yes, 2010
This thesis is involved with exploration of key changes drivers and market phenomena in the Southeast Asia and the development of new conceptual frameworks for business environmental analysis of airlines.
Kongsamutr, Navatasn
core  

The content of registered collective agreements - quantitative and qualitative analysis.

open access: yes, 2021
The Content of Registered Collective Agreements - Quantitative and Qualitative Analysis The registered collective agreements are analyzed in the master's thesis, quantitative and qualitative analysis methods are used in the research.
Jokšaitė, Agnė,
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Graphic, multimedia, and blog content presence in the Spanish academic web-space [PDF]

open access: yes, 2012
The number of pages in a website is an indicator (related to its activity) widely used in cybermetric analysis. This indicator can be disaggregated by type of content and file type.
Orduña-Malea, Enrique   +1 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Exploring a Community of Inquiry Supported by a Social Media-Based Learning Environment

open access: yesEducational Technology & Society, 2020
The Community of Inquiry (CoI) framework has been widely used in blended and online educational research, more recently being applied also to social media settings.
Elvira Popescu, Gabriel Badea
doaj  

Structuring the unstructured data: the use of content analysis

open access: yes
Content analysis is a research technique used to organise large amounts of textual data into standardised formats which allows arriving at suggestions/conclusions.
Amaratunga, Dilanthi   +2 more
core  

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