Results 131 to 140 of about 1,263,541 (299)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Harmonizing With Machines: A Quantitative Exploration of AI Coverage in German Music Magazines

open access: yesJahrbuch Musikpsychologie
In the zeitgeist of the 21st century, artificial intelligence (AI) has emerged as a focal point of discussions across various domains, from its applications in everyday life to its implications in creative fields.
Nicolas Ruth, Kristin Marie Zickler
doaj   +1 more source

#Nicotineaddiction on TikTok: A quantitative content analysis of top-viewed posts. [PDF]

open access: yesTob Induc Dis, 2022
Marynak KL   +4 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Analyzing first-semester chemistry students’ transactive talk and problem-solving activities in an intervention study through a quantitative coding manual

open access: yesFrontiers in Education
IntroductionDuring the COVID-19 pandemic, digital video conferencing formats temporarily became the new norm at universities. Due to social distancing, these environments were often the only way for students to work together.
David Johannes Hauck   +2 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Interventions in the first 1000 days to prevent childhood obesity: a systematic review and quantitative content analysis. [PDF]

open access: yesBMC Public Health, 2022
Pérez-Muñoz C   +5 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Türkiye’de Lisansüstü Halkla İlişkiler Eğitimi Üzerine Bir Araştırma: Doktora Tezlerinin Halkla İlişkiler Alanına Katkısının Niceliksel İçerik Analizi 2008-2017

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2018
Türkiye’de halkla ilişkiler alanındaki bilgi birikiminin özellikle son yirmi yılda büyük bir gelişim kaydettiği ve halkla ilişkiler mesleğinin gerek özel sektör gerek kamu kuruluşları gerekse kar amacı gütmeyen kurum ve kuruluşlarda güçlü bir yönetim ...
Başak Solmaz, Yunus Ergen, Öznur Alkan
doaj  

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