Results 41 to 50 of about 7,544,658 (347)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

How to use analysis of variance correctly——an analysis of variance for the univariate quantitative data collected from the balanced incomplete block design

open access: yesSichuan jingshen weisheng, 2022
The purpose of this paper was to introduce the model, calculation formulas and the SAS implementation of the analysis of variance for the quantitative data with balanced incomplete block design.
Hu Chunyan, Hu Liangping
doaj   +1 more source

Qualitative and Quantitative Aquatic Algal Data Compilation to Determine Macrotrends [PDF]

open access: yes, 1985
A data base of the algae of Arkansas has been initiated by the selection of a relational data base management system. The system was chosen to be readily available for microcomputers using MS- or PC-DOS.
Meyer, Richard L.
core   +1 more source

Automated analysis of quantitative image data using isomorphic functional mixed models, with application to proteomics data

open access: yes, 2011
Image data are increasingly encountered and are of growing importance in many areas of science. Much of these data are quantitative image data, which are characterized by intensities that represent some measurement of interest in the scanned images.
Baladandayuthapani, Veerabhadran   +4 more
core   +1 more source

Streaming visualisation of quantitative mass spectrometry data based on a novel raw signal decomposition method [PDF]

open access: yes, 2015
As data rates rise, there is a danger that informatics for high-throughput LC-MS becomes more opaque and inaccessible to practitioners. It is therefore critical that efficient visualisation tools are available to facilitate quality control, verification,
Beckmann   +34 more
core   +3 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior   +7 more
wiley   +1 more source

How to use χ2 test correctly——the rank sum tests and the implementation of the SAS software

open access: yesSichuan jingshen weisheng, 2021
The purpose of this article was to introduce the rank sum test and its SAS implementation. The concrete contents included the following three aspects: ①the simple linear rank test of two-sample data, ②the one-way ANOVA rank sum test of the multi-sample ...
Hu Chunyan, Hu Liangping
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

A machine learning approach to population pharmacokinetic modelling automation

open access: yesCommunications Medicine
Background Population pharmacokinetic (PopPK) models are crucial for understanding drug behaviour across populations, yet traditional development is often labour-intensive and slow.
Sam Richardson   +7 more
doaj   +1 more source

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