Results 61 to 70 of about 7,544,658 (347)
Measuring democracy among ordinary citizens—Challenges to studying democratic ideals
Frontiers in Political Science, 2022 The article addresses the methodological challenges in measuring democratic ideals on an individual level in quantitative studies. Building upon own empirical research, the study identifies several difficulties in assessing individuals' attitudes on ...
Jan-Erik Refle
doaj +1 more source
Understanding Behaviors of Attendance in Supplemental Instruction and Subsequent Academic Success in a First Year Engineering Course [PDF]
, 2019 As student retention and four-year graduation rates are of institutional and national interest and frequently referred metrics for college success, the Supplemental Instruction (SI) program aims to reduce D’s, F’s and Q drop rates in historically ...
Abraham, Nisha, Telang, Nina
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Navigating the paradigm shift of sex inclusive preclinical research and lessons learnt
Communications BiologyAfter thirty years of research highlighting the risk of the sex bias in preclinical research, we now have tangible change happening in the research landscape with a rapid increase in the proportions of studies including female and male subjects.
Natasha A. Karp
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
TerminalYouth cybercrime does not escape the difficulty of bringing visible crime into resonance, which relies on the instruments of fact-finding by the institutions in charge of dealing with real crime.
Gaël Henaff +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A quantitative approach to data-collection strategies [PDF]
Acta Crystallographica Section D Biological Crystallography, 2005 Statistical descriptors of the X-ray diffraction data set for a macromolecular crystal can be modelled using the information present in the initial diffraction images. Quantitative relationships between the crystal quality, beam apertures, oscillation width, resolution limit, redundancy and the data statistics are presented.
Bourenkov, G. P., Popov, A. N.
openaire +3 more sources
Quantitative hierarchical representation and comparison of hand grasps from electromyography and kinematic data [PDF]
, 2018 Motivation: Modeling human grasping and hand movements is important for robotics, prosthetics and rehabilitation. Several qualitative taxonomies of hand grasps have been proposed in scientific literature.
Atzori, Manfredo +4 more
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