Results 191 to 200 of about 1,152,398 (267)

Quantitative evaluation of fracture healing progression in rat femurs with modal damping factor and conventional methods. [PDF]

Front Bioeng Biotechnol
Chalikias S, Anastassopoulos G, Sarris J, Athanasopoulou S, Orkoula M, Kontoyannis C, Kostopoulos V, Psarras S, Papaioannou N, Chronopoulos E, Dontas I, Panteliou S.   +11 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Quantitative evaluation of patients' digital capability evaluated in an emergency department setting: a cross-sectional study. [PDF]

Emerg Med J
Bundsgaard Andersen L, Juul Larsen J, Marsaa K, Rosenmai G, Seemann H, Andersen Schmidt T.   +5 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Quantitative evaluation of spatially-variant deformations recovered by deep learning on clinical-like breast lesions. [PDF]

IEEE Trans Radiat Plasma Med Sci
Gao M, Raj J, Rizwan H, Barufaldi B, Krishnamoorthy S, Millardet M, Maidment ADA, Surti S, Matej S.   +8 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Semi-Quantitative Evaluation of BRCA1 Protein in Breast Tumors Using Anti-BRCA1 Antibodies: Clinical Implications. [PDF]

Int J Mol Sci
Anton SC, Nedelcu AH, Ianole V, Anton C, Danciu M, Morariu ID, Lupu A, Dascalescu G, Lupu VV, Knieling A, Nicolaiciuc D, Ciobica A, Chivasuta EA, Tirnovanu M, Dondiuc I, Ilea C, Grigore M, Anton E.   +17 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Quantitative evaluation of muscle quality and quantity using an ultrasound radio frequency signal. [PDF]

J Orthop Surg Res
Zeng L, Zhang L, Shao J, Luo J, He Q, Sun Y.   +5 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source