Results 201 to 210 of about 1,152,398 (267)

Quantitative Evaluation of Model-Informed Drug Development Implementation in China's Approved Innovative Drugs: From Policy to Practice (2018-2024). [PDF]

CPT Pharmacometrics Syst Pharmacol
Li J, Wang Z, Wei C, He R, Yao Q.
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Quantitative evaluation of sweet-responsive type II cells in mouse taste buds via biocytin uptake. [PDF]

Histochem Cell Biol
Kaetsu K, Nakagawa H, Yamasaki T, Ohtubo Y.   +3 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Can artificial intelligence help with the development of generic clinical skills when breaking bad news? A quantitative evaluation. [PDF]

Clin Med (Lond)
Armstrong ME, Bright P, Glen S, Marshall D, Jones MC.   +4 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Quantitative evaluation of computational fluid dynamics application development in the cardiovascular field through literature retrieval and bibliometric analysis. [PDF]

Biomed Eng Online
Gao F, Yang T, Wang J, Zhang B.
europepmc   +1 more source

Quantitative evaluation of cervical muscles in patients with degenerative cervical myelopathy using diffusion tensor imaging metrics. [PDF]

Bone Joint Res
Hu B, Li J, Wang J, Song Q, Ma X, Wang C, Guo H, Zheng D, Zhang WS, Yuan Y, Wang L, Han X.   +11 more
europepmc   +1 more source

Quantitative Evaluation of Coagulability in Obstetric DIC Using TEG6s for New Japanese Diagnostic Criteria of Obstetrical Disseminated Intravascular Coagulation. [PDF]

J Obstet Gynaecol Res
Matsunaga S, Nakamura E, Takai Y, Itakura A, Perinatal committee of the Japanese Society of Obstetrics and Gynecology.   +4 more
europepmc   +1 more source

Quantitative evaluation of spatial heterogeneity in dentin attrition using combined spectroscopic and elemental profiling. [PDF]

J Oral Biol Craniofac Res
Charan S, Ramadoss R, Nitya K, Sundar S, Panneer Selvam S, Hema Shree K.   +5 more
europepmc   +1 more source