Results 161 to 170 of about 60,332 (300)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

Quantifying multilateral contributions to surgical system development in low- and middle-income countries: an analysis of trends and opportunities. [PDF]

BMJ Glob Health
Bulfeta NG, Fabry S, Hyman GY, Ibbotson GC, Park KB.   +4 more
europepmc   +1 more source

Conformal Metallosaccharide Hybrid Films for Protecting Wood Surfaces From Environmental Damage

Advanced Functional Materials, EarlyView.
Ti‐ribose hybrid films fabricated by molecular layer deposition form a conformal and uniform coating on wood surfaces, which provides water repellence, dimensional stability, and resistance to acidic and alkaline environments, while preserving the natural appearance.
Wenwen Wang, Aranzazu Sierra Fernandez, Gabriele Botta, Evgenii Modin, Iva Šarić Janković, Shidong Ji, Junli Liu, Mato Knez   +7 more
wiley   +1 more source

A reproducible bibliometric-content analysis workflow for mapping research fields in computer science. [PDF]

MethodsX
Truong TC.
europepmc   +1 more source

Atomized Oxidative Polymerization as a 3D Printing Platform for Binder‐Free, Bulk Conductive Polymer Architectures

Advanced Functional Materials, EarlyView.
Co‐delivery of electrosprayed EDOT and oxidant enables bulk oxidative polymerization during layer‐by‐layer fabrication, creating stable, highly conductive 3D PEDOT structures. This Atomized Oxidative Polymerization (AOP) overcomes the surface deposition‐only and matrix‐limited conductivity of conventional Vapor Phase Polymerization (VPP) and PEDOT:PSS ...
Tazdik Patwary Plateau, Hiep Pham, Jonghyun Park   +2 more
wiley   +1 more source

Assessing family planning progress in exemplar countries: development of a conceptual framework and case study methodology. [PDF]

BMJ Glob Health
Memon ZA, Najmi H, Mian A, St-Onge Ahmad S, Islam M, Samuel K, Temmerman M, Mir AM, Sathar Z, Bhutta ZA.   +9 more
europepmc   +1 more source

On the Cohomology in Quantitative Finance

This review explores the emerging role of cohomology and topological methods inquantitative finance. We examine how algebraic structures, such as de Rham coho-mology, Cech cohomology, and spectral sequences, can be applied to model financial ˇsystems with complex dependencies, detect market anomalies, and optimize risk man-agement. The paper provides a
openaire   +1 more source

Interlayer Expansion of Bulk MoS2 via Top‐Down Organic Pillaring Enables Tunable Li+ Intercalation and Controlled Solvent Co‐Intercalation

Advanced Functional Materials, EarlyView.
Top‐down organic pillaring expands the interlayer spacing of bulk‐sized MoS2 particles while preserving the bulk morphology. Operando X‐ray diffraction and electrochemical dilatometry show that MoS2‐bulk undergoes solvent co‐intercalation in diglyme electrolyte, causing large structural expansion, while pillared, expanded MoS2 suppresses solvent uptake
Jaehoon Choi, Pakornrum Tulaphon, Franz Jacobi, Kyeonghyeon Nam, Jameela Karol, Mete B. Durukan, Christoph Scheurer, Desirée Leistenschneider, Simon Fleischmann   +8 more
wiley   +1 more source

Dynamic financial tail risk networks: A backtesting-based conditional expected shortfall approach. [PDF]

PLoS One
Zhang D, Yan X, Shen F.
europepmc   +1 more source

Review of Thermally Activated Twisted Coiled Polymer Actuators: A Materials Science Perspective

Advanced Functional Materials, EarlyView.
Thermally activated twisted and coiled polymer actuators (TCPAs) combine lightweight design, large deformation, and scalable fabrication for soft robotic and wearable applications. This review connects polymer structure, processing history, helix geometry, and thermomechanical characterization to actuator performance, highlighting current challenges in
Nadja Schenk, Lukas Benecke, Chokri Cherif, Johannes Mersch   +3 more
wiley   +1 more source