Results 1 to 10 of about 7,493,012 (309)
Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait. [PDF]
Nat Commun, 2019 Survival to extreme ages clusters within families. However, identifying genetic loci conferring longevity and low morbidity in such longevous families is challenging.
van den Berg N +8 more
europepmc +2 more sources
Molecular and quantitative genetic variation within and between populations of the declining grassland species Saxifraga granulata [PDF]
Ecology and Evolution, 2022 Formerly common plant species are expected to be particularly susceptible to recent habitat fragmentation. We studied the population genetics of 19 recently fragmented Saxifraga granulata populations (max.
Tania J. Walisch +3 more
doaj +2 more sources
The Genetic Architecture of Quantitative Traits Cannot Be Inferred from Variance Component Analysis. [PDF]
PLoS Genetics, 2016 Classical quantitative genetic analyses estimate additive and non-additive genetic and environmental components of variance from phenotypes of related individuals without knowing the identities of quantitative trait loci (QTLs). Many studies have found a
Wen Huang, Trudy F C Mackay
doaj +2 more sources
Genetic mapping of quantitative trait loci in crops
Crop Journal, 2017 Dissecting the genetic architecture of complex traits is an ongoing challenge for geneticists. Two complementary approaches for genetic mapping, linkage mapping and association mapping have led to successful dissection of complex traits in many crop ...
Yang Xu +3 more
doaj +2 more sources
Flor Yeasts Rewire the Central Carbon Metabolism During Wine Alcoholic Fermentation
Frontiers in Fungal Biology, 2021 The identification of natural allelic variations controlling quantitative traits could contribute to decipher metabolic adaptation mechanisms within different populations of the same species.
Emilien Peltier +9 more
doaj +1 more source
FEBS Open Bio, 2022 Certain cancers, such as ovarian clear cell carcinoma (OCCC), display high levels of genetic variation between patients, making it difficult to develop effective therapies.
Brandon Cona +7 more
doaj +1 more source
Current Issues in Molecular Biology, 2022 Epithelial ovarian cancer is classified into four major histological subtypes: serous, clear cell, endometrioid and mucinous. Ovarian clear cell carcinoma (OCCC) responds poorly to conventional chemotherapies and shows poor prognosis.
Ayako Kawabata +9 more
doaj +1 more source
Journal of Dairy Science, 2023 : Genotype data from dairy cattle selection programs have greatly facilitated GWAS to identify variants related to economic traits. Results can enhance the accuracy of genomic prediction, analyze more complex models that go beyond additive effects ...
G. Sahana +4 more
doaj +1 more source
Bayesian Sparse Factor Analysis of Genetic Covariance Matrices [PDF]
, 2013 Quantitative genetic studies that model complex, multivariate phenotypes are important for both evolutionary prediction and artificial selection. For example, changes in gene expression can provide insight into developmental and physiological mechanisms ...
Mukherjee, Sayan, Runcie, Daniel E
core +7 more sources
Molecular Medicine, 2017 Biobanks and national registries represent a powerful tool for genomic discovery, but rely on diagnostic codes that can be unreliable and fail to capture relationships between related diagnoses.
Thomas H. McCoy +4 more
doaj +1 more source