Results 61 to 70 of about 5,844,028 (252)

Estimating genetic diversity across the neutral genome with the use of dense marker maps [PDF]

, 2010
Background With the advent of high throughput DNA typing, dense marker maps have become available to investigate genetic diversity on specific regions of the genome. The aim of this paper was to compare two marker based estimates of the genetic diversity
Calus, M.P.L., Calus Mario PL, Jack J Windig, Bijma Piter, Windig Jack J, Krista A Engelsma, Engelsma Krista A, Bijma, P., Piter Bijma, Windig, J.J., Mario PL Calus, Engelsma, K.A.   +11 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Genetic architecture of rainbow trout survival from egg to adult [PDF]

, 2010
Survival from birth to a reproductive adult is a challenge that only robust individuals resistant to a variety of mortality factors will overcome. To assess whether survival traits share genetic architecture throughout the life cycle, we estimated ...
Paananen, T., Quiton, C., Vehvilainen, H., Kuukka-Anttila, H., Koskinen, H., Kause, A.   +5 more
core   +1 more source

Scald resistance in hybrid rye (Secale cereale): genomic prediction and GWAS

Frontiers in Plant Science
Rye (Secale cereale L.) is an important cereal crop used for food, beverages, and feed, especially in North-Eastern Europe. While rye is generally more tolerant to biotic and abiotic stresses than other cereals, it still can be infected by several ...
Mette Dam Madsen, Peter Skov Kristensen, Khalid Mahmood, Tine Thach, Marius Mohlfeld, Jihad Orabi, Pernille Sarup, Ahmed Jahoor, Mogens Støvring Hovmøller, Julian Rodriguez-Algaba, Just Jensen   +10 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Estimation of genetic variation in residual variance in female and male broiler chickens [PDF]

, 2008
In breeding programs, robustness of animals and uniformity of end product can be improved by exploiting genetic variation in residual variance. Residual variance can be defined as environmental variance after accounting for all identifiable effects.
Mulder, H. A., Vereijken, A., Veerkamp, R.F., Mulder, H.A., Hill, W. G., Veerkamp, R. F., Hill, W.G.   +6 more
core   +1 more source

Identification of Copy Number Variations and Selection Signatures in Wannan Spotted Pigs by Whole Genome Sequencing Data: A Preliminary Study

Animals
Copy number variation (CNV) is an important structural variation used to elucidate complex economic traits. In this study, we sequenced 25 Wannan spotted pigs (WSPs) to detect their CNVs and identify their selection signatures compared with those of 10 ...
Wei Zhang, Yao Jiang, Zelan Ni, Mei Zhou, Linqing Liu, Xiaoyu Li, Shiguang Su, Chonglong Wang   +7 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Phenotypic evolution and hidden speciation in Candidula unifasciata ssp. (Helicellinae, Gastropoda) inferred by 16S variation and quantitative shell traits [PDF]

, 2006
In an effort to link quantitative morphometric information with molecular data on the population level, we have analysed 19 populations of the conchologically variable land snail Candidula unifasciata from across the species range for variation in ...
Pfenninger, Markus, Magnin, Frédéric
core   +1 more source

Copy number variants selected during pig domestication inferred from whole genome resequencing

Frontiers in Veterinary Science
Over extended periods of natural and artificial selection, China has developed numerous exceptional pig breeds. Deciphering the germplasm characteristics of these breeds is crucial for their preservation and utilization.
Wei Zhang, Chengliang Xu, Mei Zhou, Linqing Liu, Zelan Ni, Shiguang Su, Chonglong Wang   +6 more
doaj   +1 more source