Results 251 to 260 of about 391,632 (299)
Problematic Internet Use in Frontotemporal Dementia: A Case Series
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The present study investigated problematic internet use (PIU) among 61 patients with frontotemporal dementia (FTD) compared to a cohort of 354 patients with mild cognitive impairment (MCI) and Alzheimer's dementia. PIU was identified in 22.9% of FTD patients compared to only 0.8% of AD patients (p < 0.001). Behaviors included compulsive social
Daniele Urso +9 more
wiley +1 more source
Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran +13 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
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2022
AbstractMost phenotypic traits are the product of many genes as well as environmental effects, and the resulting phenotypic variation is quantitative rather than qualitative. The extent to which traits are under genetic control is termed heritability, and can be estimated by analyzing the phenotypic similarity of related individuals.
Shizhong Xu
exaly +4 more sources
AbstractMost phenotypic traits are the product of many genes as well as environmental effects, and the resulting phenotypic variation is quantitative rather than qualitative. The extent to which traits are under genetic control is termed heritability, and can be estimated by analyzing the phenotypic similarity of related individuals.
Shizhong Xu
exaly +4 more sources
Sewall Wright and quantitative genetics
Genome, 1989 Some aspects of Wright's great contribution to quantitative genetics and animal breeding are reviewed in relation to current research and practice. Particular aspects discussed are as follows: the utility of his definition of inbreeding coefficient in terms of the correlation of uniting gametes; the maintenance of genetic variation in the optimum ...
William G. Hill
openaire +3 more sources
A century after Fisher: time for a new paradigm in quantitative genetics
Trends in Genetics, 2013 Quantitative genetics traces its roots back through more than a century of theory, largely formed in the absence of directly observable genotype data, and has remained essentially unchanged for decades.
Ronald M Nelson +2 more
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The quantitative genetics of transcription
Trends in Genetics, 2005Quantitative geneticists have become interested in the heritability of transcription and detection of expression quantitative trait loci (eQTLs). Linkage mapping methods have identified major-effect eQTLs for some transcripts and have shown that regulatory polymorphisms in cis and in trans affect expression.
Gibson, Greg, Weir, Bruce
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QUANTITATIVE GENETICS IN PSYCHOLOGY
British Journal of Mathematical and Statistical Psychology, 1971The following paper proposes a simple theoretical model, capable of progressive expansion, to serve as a basis for the statistical investigation of mental inheritance. Formulae are deduced for the analysis of phenotypic variances, and for estimating the covariances and correlations between relatives of different degrees of kinship.
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