Results 271 to 280 of about 4,302,850 (309)
Some of the next articles are maybe not open access.
Understanding quantitative genetic variation
Nature Reviews Genetics, 2002Until recently, it was impracticable to identify the genes that are responsible for variation in continuous traits, or to directly observe the effects of their different alleles. Now, the abundance of genetic markers has made it possible to identify quantitative trait loci (QTL)--the regions of a chromosome or, ideally, individual sequence variants ...
N H, Barton, P D, Keightley
openaire +2 more sources
2012
AbstractIn this chapter the authors consider the theoretical basis of inheritance and possible sources of phenotypic variation and familial resemblance. The investigation of the genetic basis of psychiatric disorders first requires us to examine to what extent genes and environment contribute to a given disorder or trait.
Anita Thapar, Peter McGuffin
openaire +1 more source
AbstractIn this chapter the authors consider the theoretical basis of inheritance and possible sources of phenotypic variation and familial resemblance. The investigation of the genetic basis of psychiatric disorders first requires us to examine to what extent genes and environment contribute to a given disorder or trait.
Anita Thapar, Peter McGuffin
openaire +1 more source
Quantitative Traits and Quantitative Genetics
2014In contrast with qualitative or dichotomous traits, quantitative traits are measured using quantitative or semi-quantitative variables and their inheritance is controlled by multiple genes acting independently or in association. Quantitative traits are also influenced to varying degrees by the environment and this explains why they are often designated
Jean-Louis Guénet +3 more
openaire +1 more source
Quantitative genetics: A critique
Social Biology, 1979Abstract The quantitative aspects of human genetics have hitherto been confined to (1) Mendelian categorization of qualities, which is enumerative and best applied to single‐locus conditions; and (2) Galtonian analysis, which is an examination of the first and second moments of quantities and best applied to multiple‐locus conditions.
openaire +2 more sources
Journal of Cardiovascular Pharmacology, 1988
Some of the main topics regarding the inheritance of a complex trait are discussed and the relative procedure of genetic analysis described. In particular, two complementary approaches to the study of an inherited trait in humans are outlined: the biometrical approach and the proposed methodology of dissection of the complex trait into its components ...
openaire +3 more sources
Some of the main topics regarding the inheritance of a complex trait are discussed and the relative procedure of genetic analysis described. In particular, two complementary approaches to the study of an inherited trait in humans are outlined: the biometrical approach and the proposed methodology of dissection of the complex trait into its components ...
openaire +3 more sources
2001
Most of the characteristics studied by avian ecologists relate to the external appearance of birdsiamorphology, life history, behavior, and in some cases, physiologyiathe very characteristics upon which natural selection operates. These traits are likely to be the products of tens or hundreds of loci, and their expression can be modified by numerous ...
Juha Merilä, Ben C. Sheldon
openaire +1 more source
Most of the characteristics studied by avian ecologists relate to the external appearance of birdsiamorphology, life history, behavior, and in some cases, physiologyiathe very characteristics upon which natural selection operates. These traits are likely to be the products of tens or hundreds of loci, and their expression can be modified by numerous ...
Juha Merilä, Ben C. Sheldon
openaire +1 more source
Introduction to Quantitative Genetics.
, 1962Cedric A. B. Smith, D. Falconer
semanticscholar +1 more source
Evolutionary Quantitative Genetics
Handbook of Statistical Genomics, 2019A. NIMBioS
semanticscholar +1 more source