Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Utilising quantitative methods to study the intersectionality of multiple social disadvantages in women with common mental disorders: a systematic review. [PDF]
Int J Equity Health, 2023 Alghamdi NA +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
A Bilevel DEA Model for Efficiency Evaluation and Target Setting with Stochastic Conditions
MathematicsThe effective allocation of limited resources and the establishment of targeted goals play a pivotal role in enhancing the overall efficiency of large enterprises and organizations.
Andreas C. Georgiou +4 more
doaj +1 more source
Glial cell proteome using targeted quantitative methods for potential multi-diagnostic biomarkers. [PDF]
Clin Proteomics, 2023 Kang N +10 more
europepmc +1 more source
A QUANTITATIVE METHOD FOR THE ASSAY OF INHIBITORS OF ACID GASTRIC SECRETION IN THE RAT [PDF]
, 1958 Marcus Ghosh
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Consumer Perceptions and Attitudes Towards Ultra-Processed Foods
Applied SciencesThe consumption of ultra-processed foods (UPFs) has become a central topic in discussions surrounding public health, nutrition, and consumer behaviour.
Galina Ilieva +5 more
doaj +1 more source
Indocyanine Green (ICG) and Colorectal Surgery: A Literature Review on Qualitative and Quantitative Methods of Usage. [PDF]
Medicina (Kaunas), 2023 Simion L +14 more
europepmc +1 more source