Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Increasing impact of quantitative methods and modeling in establishment of bioequivalence and characterization of drug delivery. [PDF]
CPT Pharmacometrics Syst Pharmacol, 2023 Yoon M +6 more
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A method for the quantitative fractionation of urinary 17-oxo steroids with some observations on steroid excretion during administration of ACTH and in the adrenogenital syndrome [PDF]
, 1958 R. V. Brooks
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Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
The Quantitative Determination of Radiant Heat by the Method of Electrical Compensation [PDF]
, 1894 Knut Ångström
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Molecular Oncology, EarlyView.Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban +12 more
wiley +1 more source
Quantitative Methods Used to Evaluate Impact of Combination HIV Prevention Intervention: A Methodological Systematic Review. [PDF]
AIDS Behav, 2023 Ravalihasy A +5 more
europepmc +1 more source
STUDIES ON INFLUENZA IN THE PANDEMIC OF 1957-1958. III. ISOLATION OF INFLUENZA A (ASIAN STRAIN) VIRUSES FROM INFLUENZA PATIENTS WITH PULMONARY COMPLICATIONS. DETAILS OF VIRUS ISOLATION AND CHARACTERIZATION OF ISOLATES, WITH QUANTITATIVE COMPARISON OF ISOLATION METHODS* [PDF]
, 1959 Edwin D. Kilbourne
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