Results 161 to 170 of about 6,396,260 (376)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Digital radiography image quality evaluation using various phantoms and software

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the effect of the exposure parameters on image quality (IQ) metrics of phantom images, obtained automatically using software or from visual evaluation. Methods Three commercial phantoms and a homemade phantom constructed according to the instructions given in the IAEA Human Health Series No.
Ioannis A. Tsalafoutas, Shady AlKhazzam, Virginia Tsapaki, Huda AlNaemi, Mohammed Hassan Kharita   +4 more
wiley   +1 more source

A Bilevel DEA Model for Efficiency Evaluation and Target Setting with Stochastic Conditions

Mathematics
The effective allocation of limited resources and the establishment of targeted goals play a pivotal role in enhancing the overall efficiency of large enterprises and organizations.
Andreas C. Georgiou, Konstantinos Kaparis, Eleni-Maria Vretta, Kyriakos Bitsis, George Paltayian   +4 more
doaj   +1 more source

Increasing impact of quantitative methods and modeling in establishment of bioequivalence and characterization of drug delivery. [PDF]

CPT Pharmacometrics Syst Pharmacol, 2023
Yoon M, Babiskin A, Hu M, Wu F, Raney SG, Fang L, Zhao L.   +6 more
europepmc   +1 more source

TockyLocus: Quantitative Analysis Methods for Flow Cytometric Fluorescent Timer Data [PDF]

arXiv
Fluorescent Timer proteins, which spontaneously change their emission spectra over time, are valuable tools for analyzing temporal changes in cellular activities at the single-cell level. Traditional analysis of Fluorescent Timer data has mostly relied on conventional flow cytometric methods, which lacks the sophistication needed for detailed ...
arxiv  

A RAPID AND CONVENIENT METHOD FOR THE QUANTITATIVE ELECTROLYTIC PRECIPITATION OF COPPER. [PDF]

, 1904
Théodore W. Richards, Harold Bisbee
openalex   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Combining healthiness and sustainability: An analysis of consumers’ preferences and willingness to pay for functional and sustainable snack bars

Future Foods
Despite the growing attention paid by consumers and policy makers to health and sustainability issues, contribution analyzing consumers attitude towards both health related and sustainability attributes of foods are lacking.
Anna Uliano, Marcello Stanco, Giuseppe Marotta, Concetta Nazzaro   +3 more
doaj  

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Quantitative Methods Used to Evaluate Impact of Combination HIV Prevention Intervention: A Methodological Systematic Review. [PDF]

AIDS Behav, 2023
Ravalihasy A, Ante-Testard PA, Kardas-Sloma L, Yazdanpanah Y, De Allegri M, Ridde V.   +5 more
europepmc   +1 more source