Results 181 to 190 of about 3,161,536 (308)

Quantitative methods for descriptive intersectional analysis with binary health outcomes. [PDF]

SSM Popul Health, 2022
Mahendran M, Lizotte D, Bauer GR.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Quantitative Methods for Evaluating Antibody Responses to Pneumococcal Vaccines: A Scoping Review. [PDF]

Trop Med Infect Dis
Hayashi Y, Domai FM, Dhoubhadel BG.
europepmc   +1 more source

Quantitative methods for group bibliotherapy research: a pilot study. [PDF]

Wellcome Open Res, 2022
Troscianko ET, Holman E, Carney J.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

DNA methylation heterogeneity in complex tumor microenvironment: Quantitative methods, influencing factors, and clinical implications. [PDF]

Genes Dis
Xu Y, Ma S, Xu M, Zhu H, Wang Y, Dong W, Gan J, Zhao Y, Li X, Wang S, Hu H, He J, Ning S, Zhi H.   +13 more
europepmc   +1 more source

A Systematic Review of Quantitative Methods for Evaluating Electronic Medication Administration Record and Bar-Coded Medication Administration Usability. [PDF]

Appl Clin Inform, 2023
Pruitt ZM, Kazi S, Weir C, Taft T, Busog DN, Ratwani R, Hettinger AZ.   +6 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Building Public Health Quantitative Methods Capacity and Networks in sub-Saharan Africa: An Evaluation of a Faculty Training Program. [PDF]

Glob Health Sci Pract
Ntshebe O, Anoke S, Batidzirai JM, Guure C, Muganda B, Pagano M, Semakula M, Larson E.   +7 more
europepmc   +1 more source

Comatose Patients After Cardiopulmonary Resuscitation: An Analysis Based on Quantitative Methods of EEG Reactivity. [PDF]

Front Neurol, 2022
Huang H, Su Y, Niu Z, Liu G, Li X, Jiang M.   +5 more
europepmc   +1 more source