Results 181 to 190 of about 6,427,693 (281)

A comparison of quantitative and semi-quantitative methods for assessing cartilage status and change over time; data from the osteoarthritis initiative. [PDF]

BMC Musculoskelet Disord
Ray A, Brett AD, Dube B, Bowes MA, Rowbotham E, Conaghan PG.   +5 more
europepmc   +1 more source

Integration of quantitative methods and mathematical approaches for the modeling of cancer cell proliferation dynamics.

Am J Physiol Cell Physiol, 2023
Cotner M, Meng S, Jost T, Gardner A, De Santiago C, Brock A.   +5 more
europepmc   +1 more source

Quantitative methods to study helicase, DNA polymerase, and exonuclease coupling during DNA replication. [PDF]

Methods Enzymol, 2022
Singh A, Patel SS.
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Quantitative methods for optimizing patient outcomes in liver transplantation. [PDF]

Liver Transpl
Al-Bahou R, Bruner J, Moore H, Zarrinpar A.   +3 more
europepmc   +1 more source

Quantitative methods and modeling to assess COVID-19-interrupted in vivo pharmacokinetic bioequivalence studies with two reference batches. [PDF]

CPT Pharmacometrics Syst Pharmacol, 2022
Gong Y, Feng K, Zhang P, Lee J, Pan Y, Zhang Z, Ni Z, Bai T, Yoon M, Li B, Kim CY, Fang L, Zhao L.   +12 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Assessing non-invasive quantitative methods for [¹⁸F]SynVesT-1 PET imaging of synaptic vesicle glycoprotein 2A in the rat brain. [PDF]

Eur J Nucl Med Mol Imaging
Berckmans L, Schrauwen C, Miranda A, Staelens S, Bertoglio D.   +4 more
europepmc   +1 more source

The brief overview, antivirus and anti-SARS-CoV-2 activity, quantitative methods, and pharmacokinetics of cepharanthine: a potential small-molecule drug against COVID-19. [PDF]

Front Pharmacol, 2023
Xia B, Zheng L, Li Y, Sun W, Liu Y, Li L, Pang J, Chen J, Li J, Cheng H.   +9 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source