Results 31 to 40 of about 2,957,746 (274)

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Scaling production and improving efficiency in DEA: an interactive approach

open access: yesJournal of Industrial Engineering International, 2017
DEA models help a DMU to detect its (in-)efficiency and to improve activities, if necessary. Efficiency is only one economic aim for a decision-maker; however, up- or downsizing might be a second one.
Wilhelm Rödder   +2 more
doaj   +1 more source

The efficiency of private pension companies using dynamic data envelopment analysis

open access: yesQuantitative Finance and Economics, 2020
Saving plays an important role in economics. Private Pension System (PPS) helps individuals make savings and contribute to the nation’s economy. Therefore, it is important to know the performance of Private Pension Companies (PPCs) that manage the ...
Yonca Erdem Demirtaş   +1 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Assessment of care provision integration in a community-based mental health system: balanced care model implementation in Andalusia (Spain)

open access: yesBMC Public Health
Background Andalusia is the second largest region in Spain, and it has developed a comprehensive mental health (MH) plan that encourages the consolidation of the balanced care model.
Diego Diaz-Milanes   +4 more
doaj   +1 more source

Analysis of ownership network of European companies using gravity models

open access: yesApplied Network Science, 2022
Social network analysis is increasingly applied to modeling regional relationships. However, in this scenario, we cannot ignore the geographical economic and technological nature of the relationships.
Zsolt Tibor Kosztyán   +2 more
doaj   +1 more source

A Stochastic Bilevel DEA-Based Model for Resource Allocation

open access: yesComputer Sciences & Mathematics Forum, 2023
The optimal allocation of limited resources along with output target setting are critical in pursuing the sustainability and competitiveness of organizations.
Eleni-Maria Vretta   +4 more
doaj   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Exploring the Influence of Crime on NEET Rates: A Regional Analysis of Italy

open access: yesMerits
The occurrence of criminal activities has the potential to hinder socioeconomic advancement, preventing individuals from investing in human capital and pursuing employment opportunities.
Iacopo Odoardi   +3 more
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

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