Results 51 to 60 of about 6,396,260 (376)

Students' developing knowledge in a subject discipline: insights from combining quantitative and qualitative methods [PDF]

, 2005
In this paper we describe an example of research that combined quantitative and qualitative methods in order to investigate students' developing mathematical reasoning over time and to identify factors that were influential in this ...
Healy, Lulu, Hoyles, Celia, Küchemann, Dietmar, Yang, Min   +3 more
core   +3 more sources

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Quantitative stability for the nonlocal overdetermined Serrin problem [PDF]

arXiv, 2023
We establish quantitative stability for the nonlocal Serrin overdetermined problem, via the method of the moving planes. Interestingly, our stability estimate is even better than those obtained so far in the classical setting (i.e., for the classical Laplacian) via the method of the moving planes.
arxiv  

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

Rapid quantitative pharmacodynamic imaging by a novel method: theory, simulation testing and proof of principle [PDF]

PeerJ 1:e117, 2013, 2013
Pharmacological challenge imaging has mapped, but rarely quantified, the sensitivity of a biological system to a given drug. We describe a novel method called rapid quantitative pharmacodynamic imaging. This method combines pharmacokinetic-pharmacodynamic modeling, repeated small doses of a challenge drug over a short time scale, and functional imaging
arxiv   +1 more source

Quantitative Methods [PDF]

, 2018
Quantitative Methods ...
Elkhouly, Ahmed
core   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

A revision of Altman Z-Score model and a comparative analysis of Turkish companies' financial distress prediction

National Accounting Review, 2021
This paper aims to predict companies' financial distress situation with the use of four different models; Altman Z score, Revised Altman Z Score (Linear Discriminant Analysis) and Quadratic Discriminant Analysis, Random Forest Machine Learning Model with
Zeynep Cındık, Ismail H. Armutlulu
doaj   +1 more source

Contrast-Agnostic Groupwise Registration by Robust PCA for Quantitative Cardiac MRI [PDF]

arXiv, 2023
Quantitative cardiac magnetic resonance imaging (MRI) is an increasingly important diagnostic tool for cardiovascular diseases. Yet, co-registration of all baseline images within the quantitative MRI sequence is essential for the accuracy and precision of quantitative maps.
arxiv