Results 51 to 60 of about 36,219,545 (383)

Evaluating Variable Selection Methods in a Classification Framework: A Simulation Study

Epidemiology, Biostatistics and Public Health
INTRODUCTION Variable selection is a common step in clinical research, where large datasets often include many, potentially highly correlated, variables. The main objective is to identify the most relevant predictors for an outcome, thereby enhancing
Samuele Minari, Dario Pescini, Antonella Zambon, Davide Soranna   +3 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

A comparison of quantitative methods for clinical imaging with hyperpolarized 13C‐pyruvate

NMR in Biomedicine, 2016
Dissolution dynamic nuclear polarization (DNP) enables the metabolism of hyperpolarized 13C‐labelled molecules, such as the conversion of [1‐13C]pyruvate to [1‐13C]lactate, to be dynamically and non‐invasively imaged in tissue.
C. Daniels, M. McLean, R. Schulte, F. Robb, A. Gill, N. McGlashan, M. Graves, M. Schwaiger, D. Lomas, K. Brindle, F. Gallagher   +10 more
semanticscholar   +1 more source

Integrating case study and survey research methods: An example in information systems [PDF]

, 1994
The case for combining research methods generally, and more specifically that for combining qualitative and quantitative methods, is strong. Yet, research designs that extensively integrate both fieldwork (e.g. case studies) and survey research are rare.
Gable, Guy G.
core   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Assessment of care provision integration in a community-based mental health system: balanced care model implementation in Andalusia (Spain)

BMC Public Health
Background Andalusia is the second largest region in Spain, and it has developed a comprehensive mental health (MH) plan that encourages the consolidation of the balanced care model.
Diego Diaz-Milanes, Nerea Almeda, Maria Luisa Rodero-Cosano, Jose A. Salinas-Perez, Carlos R. Garcia-Alonso   +4 more
doaj   +1 more source

Consumers’ acceptance and willingness to pay for enriched foods: Evidence from a choice experiment in Italy

Future Foods
Over the last decades, consumer has evolved becoming increasingly responsible, showing a preference for those foods having a positive impact on health, society and environment.
Concetta Nazzaro, Marcello Stanco, Anna Uliano, Giuseppe Marotta   +3 more
doaj   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

FEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic, Morana Dulic, Ita Gruic‐Sovulj   +2 more
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Exploring the Influence of Crime on NEET Rates: A Regional Analysis of Italy

Merits
The occurrence of criminal activities has the potential to hinder socioeconomic advancement, preventing individuals from investing in human capital and pursuing employment opportunities.
Iacopo Odoardi, Dario D’Ingiullo, Ada Di Nucci, Davide Quaglione   +3 more
doaj   +1 more source