Results 61 to 70 of about 16,916,210 (280)
Background: Knee pain represents the second most common musculoskeletal disorder after low back pain [1]. Knee osteoarthritis (OA) represents the leading cause of knee pain, as well as the most common site for OA, with a projected increase of 74.9 ...
Stefano Giuseppe Lazzarini +2 more
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Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Introduction Cardiovascular and cerebrovascular diseases represent one of the leading causes of morbidity and mortality in Italy [1]. Acute events such as myocardial infarction and ischemic stroke have a significant clinical, economic, and social ...
Ginevra Torrigiani +2 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Despite the growing attention paid by consumers and policy makers to health and sustainability issues, contribution analyzing consumers attitude towards both health related and sustainability attributes of foods are lacking.
Anna Uliano +3 more
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Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The change-point model is an established methodology for the construction of self-starting control charts. Change-point charts are often nonparametric in order to be independent from any specific assumptions about the process distribution.
Claudio Giovanni Borroni +2 more
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Background: Joinpoint regression analysis is usually applied to study varying trends over time in order to identify the time point(s) in which the trend significantly changes.
Eleonora Pagan +6 more
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A QUANTITATIVE ELECTROCARDIOGRAPHIC METHOD [PDF]
H E S, PEARSON, L M, GERLIS
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The Bradford Method for Protein Quantitation
A rapid and accurate method for the estimation of protein concentration is essential in many fields of protein study. The Lowry method ( Chapter 1 in vol. 1 of this series) has been widely used, but is susceptible to interference from a wide range of compounds commonly present in biological extracts.
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