Results 61 to 70 of about 16,916,210 (280)

Effectiveness of Laser Therapy in Adults with Knee Osteoarthritis: A Bivariate Meta-Analysis of Placebo-Controlled Randomized Controlled Trials

open access: yesEpidemiology, Biostatistics and Public Health
Background: Knee pain represents the second most common musculoskeletal disorder after low back pain [1]. Knee osteoarthritis (OA) represents the leading cause of knee pain, as well as the most common site for OA, with a projected increase of 74.9 ...
Stefano Giuseppe Lazzarini   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Epidemiology of Acute Cardiovascular and Cerebrovascular Events in the Lombardy Region: A Population-Based Study (2015–2021)

open access: yesEpidemiology, Biostatistics and Public Health
Introduction Cardiovascular and cerebrovascular diseases represent one of the leading causes of morbidity and mortality in Italy [1]. Acute events such as myocardial infarction and ischemic stroke have a significant clinical, economic, and social ...
Ginevra Torrigiani   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Combining healthiness and sustainability: An analysis of consumers’ preferences and willingness to pay for functional and sustainable snack bars

open access: yesFuture Foods
Despite the growing attention paid by consumers and policy makers to health and sustainability issues, contribution analyzing consumers attitude towards both health related and sustainability attributes of foods are lacking.
Anna Uliano   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Dynamic Window Approach as a Tool to Improve Performance of Nonparametric Self-Starting Control Charts

open access: yesMathematics
The change-point model is an established methodology for the construction of self-starting control charts. Change-point charts are often nonparametric in order to be independent from any specific assumptions about the process distribution.
Claudio Giovanni Borroni   +2 more
doaj   +1 more source

Joinpoint regression analysis with time-on-study as time-scale. Application to three Italian population-based cohort studies

open access: yesEpidemiology, Biostatistics and Public Health, 2017
Background: Joinpoint regression analysis is usually applied to study varying trends over time in order to identify the time point(s) in which the trend significantly changes.
Eleonora Pagan   +6 more
doaj   +1 more source

The Bradford Method for Protein Quantitation

open access: yes, 1996
A rapid and accurate method for the estimation of protein concentration is essential in many fields of protein study. The Lowry method ( Chapter 1 in vol. 1 of this series) has been widely used, but is susceptible to interference from a wide range of compounds commonly present in biological extracts.
openaire   +3 more sources

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