Results 81 to 90 of about 1,313,775 (264)

How ESG corporate reputation affects sustainability premiums in the insurance industry

Frontiers in Applied Mathematics and Statistics
Based on increasing ESG awareness, executives, and investment professionals consider ESG factors in strategic and operational decisions. Like other companies, insurers recognize that the ESG transition offers opportunities for long-term value creation ...
Maria Carannante, Valeria D'Amato, Maria Sole Staffa   +2 more
doaj   +1 more source

Quantitative Models of Lipid Transfer and Membrane Contact Formation. [PDF]

Contact (Thousand Oaks), 2022
Zhang Y, Ge J, Bian X, Kumar A.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Predictive modelling of the effectiveness of vaccines against COVID-19 in Bogotá: Methodological innovation involving different variants and computational optimisation efficiency

Heliyon
The uncertainty associated with the future of viruses such as SARS-CoV-2 poses a challenge to public health officials because of its implications for welfare, economics and population health. In this document, we develop an age-stratified epidemiological-
Oscar Espinosa, Lisa White, Valeria Bejarano, Ricardo Aguas, Duván Rincón, Laura Mora, Antonio Ramos, Cristian Sanabria, Jhonathan Rodríguez, Nicolás Barrera, Carlos Álvarez-Moreno, Jorge Cortés, Carlos Saavedra, Adriana Robayo, Bo Gao, Oscar Franco   +15 more
doaj   +1 more source

Quantitative models for building and growing fated small cell networks. [PDF]

Interface Focus, 2022
Diegmiller R, Nunley H, Shvartsman SY, Imran Alsous J.   +3 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Quantitative models in urban planning [PDF]

مطالعات مدیریت بهبود و تحول, 1995
مدیریت جامعه باید با انتخاب یک سیستم پویا علاوه بر عوامل و پارامترهای معقول در بخش های کشاورزی، صنایع و خدمات و به منظور جلوگیری از آلودگی محیط زیست، تلاش برای دستیابی به منابع جدید، تجدید حیات موجود، توزیع بهینه جمعیت و ...، جامعه را به طرف کمال مطلوب ...
ali khaaki firouzabadi
doaj  

Toward Quantitative Models in Safety Assessment: A Case Study to Show Impact of Dose-Response Inference on hERG Inhibition Models. [PDF]

Int J Mol Sci, 2022
Melnikov F, Anger LT, Hasselgren C.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A literature review on quantitative models for supply chain risk management: Can they be applied to pandemic disruptions? [PDF]

Comput Ind Eng, 2022
Rinaldi M, Murino T, Gebennini E, Morea D, Bottani E.   +4 more
europepmc   +1 more source