Results 111 to 120 of about 857,162 (283)

Quantitative hard x-ray phase contrast imaging of micropipes in SiC

open access: yesAIP Advances, 2013
Peculiarities of quantitative hard x-ray phase contrast imaging of micropipes in SiC are discussed. The micropipe is assumed as a hollow cylinder with an elliptical cross section.
V. G. Kohn, T. S. Argunova, J. H. Je
doaj   +1 more source

Quantitative phase imaging in biomedicine

open access: yesConference on Lasers and Electro-Optics 2012, 2012
Quantitative phase imaging, i.e., measuring the map of pathlength shifts due to the specimen of interest, has been developing rapidly over the past decade. The main methods and exciting applications to biomedicine will be reviewed.
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Label-free functional analysis of root-associated microbes with dynamic quantitative oblique back-illumination microscopy

open access: yesScientific Reports
The increasing global demand for food, coupled with concerns about the environmental impact of synthetic fertilizers, underscores the urgency of developing sustainable agricultural practices.
Caroline E. Serafini   +6 more
doaj   +1 more source

Breakthroughs in Photonics 2013: Quantitative Phase Imaging: Metrology Meets Biology

open access: yesIEEE Photonics Journal, 2014
Quantitative phase imaging (QPI) is an emerging optical approach that measures the optical path length of a transparent specimen noninvasively. Therefore, it is suitable for studying unstained biological tissues and cells with high sensitivity and ...
Taewoo Kim   +3 more
doaj   +1 more source

Quantitative phase imaging using grating-based quadrature phase interferometer [PDF]

open access: yes, 2007
In this paper, we report the use of holographic gratings, which act as the free-space equivalent of the 3x3 fiber-optic coupler, to perform full field phase imaging.
Cui, Xiquan   +4 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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