Results 91 to 100 of about 9,244,583 (282)

Simple and fast spectral domain algorithm for quantitative phase imaging of living cells with digital holographic microscopy

, 2017
We present a simple and fast phase aberration compensation method in digital holographic microscopy (DHM) for quantitative phase imaging of living cells.
Baoli Yao (386384), Steffi Ketelhut (633588), Junwei Min (709502), Ketelhut, Steffi, Yao, Baoli, Min, Junwei, Greve, Burkhard, Björn Kemper (633590), Burkhard Greve (125341), Engwer, Christian, Kemper, Bjoern, Christian Engwer (3959855)   +11 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Quantitative phase imaging through an ultra-thin lensless fiber endoscope

, 2021
Quantitative phase imaging (QPI) is a label-free technique providing both morphology and quantitative biophysical information in biomedicine. However, applying such a powerful technique to in vivo pathological diagnosis remains challenging.
Nektarios Koukourakis (10155728), Song Wu (36667), Jiawei Sun (772107), Salvatore Girardo (517120), Jochen Guck (131657), Liangcai Cao (3942134), Ruchi Goswami (14411616), Juergen W. Czarske (14411619), Jiachen Wu (3984905)   +8 more
core   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Spectral modulation interferometry for quantitative phase imaging

Biomedical Optics Express, 2015
We propose a spectral-domain interferometric technique, termed spectral modulation interferometry (SMI), and present its application to high-sensitivity, high-speed, and speckle-free quantitative phase imaging. In SMI, one-dimensional complex field of an object is interferometrically modulated onto a broadband spectrum.
Ruibo, Shang, Shichao, Chen, Chengshuai, Li, Yizheng, Zhu   +3 more
openaire   +2 more sources

An evaluation of prospective motion correction (PMC) for high resolution quantitative MRI. [PDF]

, 2015
Quantitative imaging aims to provide in vivo neuroimaging biomarkers with high research and diagnostic value that are sensitive to underlying tissue microstructure.
Weiskopf, N, Weiskopf, N. ; https://orcid.org/, Josephs, O, Oliver Josephs, Herbst, M, Martina F. Callaghan, Zaitsev, M., Weiskopf, Nikolaus, Michael eHerbst, Martina F Callaghan, Nikolaus eWeiskopf, Zaitsev, M, Todd, N., Nick Todd, Herbst, M., Herbst, Michael, Maxim eZaitsev, Nikolaus Weiskopf, Michael Herbst, Callaghan, M., Nick eTodd, Maxim Zaitsev, Josephs, O., Callaghan, Martina F., Todd, Nick, Callaghan, MF, Josephs, Oliver, Todd, N, Oliver eJosephs, Zaitsev, Maxim   +29 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Lab on chip optical imaging of biological sample by quantitative phase microscopy

, 2015
SIRE(opens in a new window)|View at Publisher| CSV export | Download | Add to List | More... Progress in Biomedical Optics and Imaging - Proceedings of SPIE Volume 9336, 2015, Article number 933625 1st Conference on Quantitative Phase Imaging ...
Merola, F., NETTI, PAOLO ANTONIO, Ferraro, P., P. Memmolo, L. Miccio, O. Gennari, Mugnano, M., P. Ferraro, P. A. Netti, Memmolo, P., M. Mugnano, Miccio, L., Gennari, O., F. Merola, Mugnano M, Ferraro P, Memmolo P, Gennari O, Netti PA, Miccio L, Merola F   +20 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Open-source implementation of polarisation-resolved single-shot differential phase contrast microscopy (pDPC) on a modular openFrame-based microscope

HardwareX
We recently demonstrated polarisation differential phase contrast microscopy (pDPC) as a robust, low-cost single-shot implementation of (semi)quantitative phase imaging based on differential phase microscopy. pDPC utilises a polarisation-sensitive camera
Huihui Liu, Sunil Kumar, Edwin Garcia, William Flanagan, Jonathan Lightley, Christopher Dunsby, Paul M.W. French   +6 more
doaj   +1 more source