Results 91 to 100 of about 387,608 (286)

Lab on chip optical imaging of biological sample by quantitative phase microscopy

, 2015
SIRE(opens in a new window)|View at Publisher| CSV export | Download | Add to List | More... Progress in Biomedical Optics and Imaging - Proceedings of SPIE Volume 9336, 2015, Article number 933625 1st Conference on Quantitative Phase Imaging ...
Merola, F., NETTI, PAOLO ANTONIO, Ferraro, P., P. Memmolo, L. Miccio, O. Gennari, Mugnano, M., P. Ferraro, P. A. Netti, Memmolo, P., M. Mugnano, Miccio, L., Gennari, O., F. Merola   +13 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Simple and fast spectral domain algorithm for quantitative phase imaging of living cells with digital holographic microscopy

, 2017
We present a simple and fast phase aberration compensation method in digital holographic microscopy (DHM) for quantitative phase imaging of living cells.
Baoli Yao (386384), Steffi Ketelhut (633588), Junwei Min (709502), Ketelhut, Steffi, Yao, Baoli, Min, Junwei, Greve, Burkhard, Björn Kemper (633590), Burkhard Greve (125341), Engwer, Christian, Kemper, Bjoern, Christian Engwer (3959855)   +11 more
core   +1 more source

Exploring T*2 decay : new methods for short echo time imaging and fat-water quantification [PDF]

, 2013
The major advantage of magnetic resonance imaging (MRI) over other imaging modalities like computed tomography (CT) is that it does not utilize ionizing radiation.
Deligianni, Xeni
core   +1 more source

Quantitative phase imaging in biomedicine

Conference on Lasers and Electro-Optics 2012, 2012
Quantitative phase imaging, i.e., measuring the map of pathlength shifts due to the specimen of interest, has been developing rapidly over the past decade. The main methods and exciting applications to biomedicine will be reviewed.
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Open-source implementation of polarisation-resolved single-shot differential phase contrast microscopy (pDPC) on a modular openFrame-based microscope

HardwareX
We recently demonstrated polarisation differential phase contrast microscopy (pDPC) as a robust, low-cost single-shot implementation of (semi)quantitative phase imaging based on differential phase microscopy. pDPC utilises a polarisation-sensitive camera
Huihui Liu, Sunil Kumar, Edwin Garcia, William Flanagan, Jonathan Lightley, Christopher Dunsby, Paul M.W. French   +6 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Quantitative polarized phase microscopy for birefringence imaging

Optics Express, 2007
A novel application of quantitative phase imaging under linearly polarized light is introduced for studying unstained anisotropic live cells. The method is first validated as a technique for mapping the two-dimensional retardation distribution of a well-characterized optical fiber and is then applied to the characterization of unstained isolated ...
Dragomir, Nicoleta, Goh, Xiao Ming, Curl, Claire L, Delbridge, Lea M. D, Roberts, Ann   +4 more
openaire   +3 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source