Quantitative structureâactivity relationship (QSAR) analysis of aromatic effector specificity in NtrC-like transcriptional activators from aromatic oxidizing bacteria [PDF]
FEMS Microbiology Letters, 2003 A quantitative structure-activity relationship (QSAR) approach was taken to provide mechanistic insights into the interaction between the chemical structure of inducing compounds and the transcriptional activation of aromatic monooxygenase operons among the XylR/DmpR subclass of bacterial NtrC-like transcriptional regulators. Compared to XylR and DmpR,
Park, Joonhong +3 more
openaire +3 more sources
QSAR studies for the acute toxicity of nitrobenzenes to the Tetrahymena pyriformis [PDF]
Journal of the Serbian Chemical Society, 2014 Quantitative structure-activity relationship (QSAR) models play a key role in finding the relationship between molecular structures and the toxicity of nitrobenzenes to Tetrahymena pyriformis.
Wang Dan-Dan +3 more
doaj +1 more source
Design of cinnamaldehyde amino acid Schiff base compounds based on the quantitative structure–activity relationship [PDF]
Royal Society Open Science, 2017 Cinnamaldehyde amino acid Schiff base (CAAS) is a new class of safe, bioactive compounds which could be developed as potential antifungal agents for fungal infections.
Hui Wang +6 more
doaj +1 more source
Beni-Suef University Journal of Basic and Applied Sciences, 2020 Background Prostate cancer is the most common non-cutaneous cancer in males and accounts for about 4% of all cancer-related deaths in males annually.
Fabian A. Ikwu +2 more
doaj +1 more source
Correlation between the lipophilicity and antifungal activity of some benzoxazole derivatives [PDF]
Acta Periodica Technologica, 2010 In the present work, a quantitative relationship between the lipophilicity and antifungal activity of some benzoxazole derivatives against Candida albicans was investigated by using QSAR (quantitative structure-activity relationship) analyses.
Podunavac-Kuzmanović Sanja O. +1 more
doaj +1 more source
Quantitative Structure Activity Relationship Models for the Antioxidant Activity of Polysaccharides. [PDF]
PLoS ONE, 2016 In this study, quantitative structure activity relationship (QSAR) models for the antioxidant activity of polysaccharides were developed with 50% effective concentration (EC50) as the dependent variable.
Zhiming Li +3 more
doaj +1 more source
مجله دانشکده پزشکی اصفهان, 2020 Background: Due to the growing population of the elderly and the increasing trend of Alzheimer's disease, evaluation of acetylcholinesterase (AChE) and butyl cholinesterase (BChE) inhibitors, as major causes of Alzheimer's disease, is essential.
Fahimeh Motamedi +2 more
doaj +1 more source
Quantitative structure-activity relationship modelling of influenza M2 ion channels inhibitors [PDF]
Journal of the Serbian Chemical Society, 2021 A series of adamantane derivatives (rimantadine and amantadine) incorporating amino-acid residues are investigated by simplex representation of molecular structure (SiRMS) approach in order to found correlation between chemical structures of investigated
Stankova Ivanka G. +7 more
doaj +1 more source
Quantitative Structure–Activity Relationship Evaluation of MDA-MB-231 Cell Anti-Proliferative Leads
Molecules, 2021 In the present endeavor, for the dataset of 219 in vitro MDA-MB-231 TNBC cell antagonists, a (QSAR) quantitative structure–activity relationships model has been carried out.
Ajaykumar Gandhi +5 more
doaj +1 more source
, 2021 The diversity of RNA structural elements and their documented role in human diseases make RNA an attractive therapeutic target. However, progress in drug discovery and development has been hindered by challenges in the determination of high-resolution ...
Martina, Zafferani +3 more
core +1 more source