Results 31 to 40 of about 357,921 (162)

LIPOPHILICITY AND ANTIFUNGAL ACTIVITY OF SOME 2-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2011
In the present paper, the antifungal activity of some 2-methyl and 2-amino-benzimidazole derivatives was evaluated against yeast Saccharomyces cere¬visiae. The tested compounds displayed in vitro antifungal activity and mini¬mum inhibitory concentration (
SANJA O. PODUNAVAC-KUZMANOVIĆ   +1 more
doaj  

Quantitative structure-activity relationship to elucidate human CYP2A6 inhibition by organosulfur compounds

open access: yesADMET and DMPK, 2019
CYP2A6 is a human enzyme responsible for the metabolic elimination of nicotine, and it is also involved in the activation of procarcinogenic nitrosamines, especially those present in tobacco smoke.
Daniela Andrea Ramirez   +3 more
doaj   +1 more source

Toward Novel Antioxidant Drugs: Quantitative Structure-Activity Relationship Study of Eugenol Derivatives

open access: yesWalisongo Journal of Chemistry, 2021
The study of the Quantitative Structure-Activity Relationship (QSAR) of eugenol compound and its derivatives towards antioxidant activities was conducted using electronic and molecular descriptors.
Priyagung Dhemi Widiakongko   +1 more
doaj   +1 more source

Biological activity, quantitative structure–activity relationship analysis, and molecular docking of xanthone derivatives as anticancer drugs

open access: yesDrug Design, Development and Therapy, 2018
Isnatin Miladiyah,1,2 Jumina Jumina,3 Sofia Mubarika Haryana,4 Mustofa Mustofa5 1Pharmacology Department, Faculty of Medicine, Islamic University of Indonesia, 2Doctorate Program of Medical Science and Health, Faculty of Medicine, 3Chemistry Department,
Miladiyah I   +3 more
doaj  

A Quantitative Structure–Activity Relationship Study of the Anabolic Activity of Ecdysteroids

open access: yesComputation
Phytoecdysteroids represent a class of naturally occurring substances known for their diverse biological functions, particularly their strong ability to stimulate protein anabolism.
Durbek Usmanov   +4 more
doaj   +1 more source

Quantitative structure-activity relationship of some 1-benzylbenzimidazole derivatives as antifungal agents [PDF]

open access: yesActa Periodica Technologica, 2007
In the present study, the antifungal activity of some 1-benzylbenzimidazole derivatives against yeast Saccharomyces cerevisiae was investigated. The tested benzimidazoles displayed in vitro antifungal activity and minimum inhibitory concentration (MIC ...
Podunavac-Kuzmanović Sanja O.   +2 more
doaj   +1 more source

Cinnamic Derivatives as Antitubercular Agents: Characterization by Quantitative Structure–Activity Relationship Studies

open access: yesMolecules, 2020
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), remains one of the top ten causes of death worldwide and the main cause of mortality from a single infectious agent.
Cátia Teixeira   +4 more
doaj   +1 more source

Quantitative structure–activity relationship study of antitubercular fluoroquinolones [PDF]

open access: yesMolecular Diversity, 2010
Quantitative structure-activity relationship study on three diverse sets of structurally similar fluoroquinolones was performed using a comprehensive set of molecular descriptors. Multiple linear regression technique was applied as a preprocessing tool to find the set of relevant descriptors (10) which are subsequently used in the artificial neural ...
Minovski, Nikola   +2 more
openaire   +2 more sources

An assessment of mutagenicity of chemical substances by (quantitative) structure–activity relationship

open access: yesGenes and Environment, 2020
Currently, there are more than 100,000 industrial chemicals substances produced and present in our living environments. Some of them may have adverse effects on human health.
Masamitsu Honma
doaj   +1 more source

Comparison of Quantitative Structure-Activity Relationship Model Performances on Carboquinone Derivatives

open access: yesThe Scientific World Journal, 2009
Quantitative structure-activity relationship (qSAR) models are used to understand how the structure and activity of chemical compounds relate. In the present study, 37 carboquinone derivatives were evaluated and two different qSAR models were developed ...
Sorana D. Bolboaca, Lorentz Jäntschi
doaj   +1 more source

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