The whole-brain pattern of magnetic susceptibility perturbations in Parkinson's disease [PDF]
Although iron-mediated oxidative stress has been proposed as a potential pathomechanism in Parkinson's disease, the global distribution of iron accumulation in Parkinson's disease has not yet been elucidated.
Acosta-Cabronero, J +6 more
core +1 more source
Tissue magnetic susceptibility mapping as a marker of tau pathology in Alzheimer's disease. [PDF]
Alzheimer's disease is connected to a number of other neurodegenerative conditions, known collectively as 'tauopathies', by the presence of aggregated tau protein in the brain.
Ahmed, Z +15 more
core +1 more source
Streaking artifact suppression of quantitative susceptibility mapping reconstructions via L1‐norm data fidelity optimization (L1‐QSM) [PDF]
PurposeThe presence of dipole‐inconsistent data due to substantial noise or artifacts causes streaking artifacts in quantitative susceptibility mapping (QSM) reconstructions. Often used Bayesian approaches rely on regularizers, which in turn yield reduced sharpness.
Carlos Milovic +5 more
openaire +4 more sources
Disrupted iron regulation in the brain and periphery in cocaine addiction [PDF]
Stimulant drugs acutely increase dopamine neurotransmission in the brain, and chronic use leads to neuroadaptive changes in the mesolimbic dopamine system and morphological changes in basal ganglia structures.
Acosta-Cabronero, J +7 more
core +1 more source
Simultaneous Quantitative MRI Mapping of T1, T2* and Magnetic Susceptibility with Multi-Echo MP2RAGE. [PDF]
The knowledge of relaxation times is essential for understanding the biophysical mechanisms underlying contrast in magnetic resonance imaging. Quantitative experiments, while offering major advantages in terms of reproducibility, may benefit from ...
Kober, T. +3 more
core +7 more sources
Slowly expanding/evolving lesions as a magnetic resonance imaging marker of chronic active multiple sclerosis lesions. [PDF]
BACKGROUND:Chronic lesion activity driven by smoldering inflammation is a pathological hallmark of progressive forms of multiple sclerosis (MS). OBJECTIVE:To develop a method for automatic detection of slowly expanding/evolving lesions (SELs) on ...
Arnold, Douglas L +8 more
core +2 more sources
Ex-vivo quantitative susceptibility mapping of human brain hemispheres. [PDF]
Ex-vivo brain quantitative susceptibility mapping (QSM) allows investigation of brain characteristics at essentially the same point in time as histopathologic examination, and therefore has the potential to become an important tool for determining the ...
Arnold M Evia +8 more
doaj +1 more source
Quantitative susceptibility mapping (QSM) inevitably suffers from streaking artifacts caused by zeros on the conical surface of the dipole kernel in k-space.
Ahn, Hyun-Seo +2 more
core +1 more source
A comparison of phase imaging and quantitative susceptibility mapping in the imaging of multiple sclerosis lesions at ultrahigh field [PDF]
Objective The aim of this study was to compare the use of high-resolution phase and QSM images acquired at ultra-high field in the investigation of multiple sclerosis (MS) lesions with peripheral rings, and to discuss their usefulness for drawing ...
A Eissa +44 more
core +1 more source
Exploring linearity of deep neural network trained QSM: QSMnet+
Recently, deep neural network-powered quantitative susceptibility mapping (QSM), QSMnet, successfully performed ill-conditioned dipole inversion in QSM and generated high-quality susceptibility maps.
Woojin Jung +7 more
doaj +1 more source

