Results 51 to 60 of about 2,739 (132)

Single‐Shot 2D Radial Echo Planar Imaging for Functional MRI

Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1245-1260, September 2026.
ABSTRACT Purpose To develop a novel single‐shot radial echo planar imaging (ss‐rEPI) technique for rapid, distortion‐free brain imaging in functional MRI experiments. Methods Radial multi‐gradient echo (radial mGRE) data were acquired on a 3T clinical scanner using a 2D ss‐rEPI readout with small golden‐angle rotations between echoes.
Christoph A. Rettenmeier, Zidan Yu, Krystalyn Edwards‐Calma, Kai Tobias Block, V. Andrew Stenger   +4 more
wiley   +1 more source

Targeting progressive multiple sclerosis: Toward mechanism‐informed precision medicine

Journal of Internal Medicine, Volume 300, Issue 3, Page 238-257, September 2026.
Abstract Multiple sclerosis has undergone a therapeutic revolution over the past three decades. Randomized clinical trials and real‐world data demonstrate that modern disease‐modifying therapies substantially reduce relapse rates and acute inflammatory activity detected by magnetic resonance imaging (MRI).
Fredrik Piehl, Gonçalo Castelo‐Branco, Maja Jagodic, Tomas Olsson   +3 more
wiley   +1 more source

Advances in neuroimaging applications of quantitative susceptibility mapping

Meta-Radiology
This review article delves into the advancements of quantitative susceptibility mapping (QSM) in neuroimaging, highlighting its utility in detecting and quantifying magnetic susceptibility differences in tissues, particularly for paramagnetic substances ...
Shuxin Ma, Wencan Fu, Chao Chai, Huiying Wang, Ke Lv, Chenxi Zhao, E. Mark Haacke, Sagar Buch, Shuang Xia   +8 more
doaj   +1 more source

Diagnostic accuracy of semiautomatic lesion detection plus quantitative susceptibility mapping in the identification of new and enhancing multiple sclerosis lesions

NeuroImage: Clinical, 2018
Purpose: To evaluate the diagnostic accuracy of a novel non-contrast brain MRI method based on semiautomatic lesion detection using T2w FLAIR subtraction image, the statistical detection of change (SDC) algorithm (T2w + SDC), and quantitative ...
Shun Zhang, Thanh D. Nguyen, Yize Zhao, Susan A. Gauthier, Yi Wang, Ajay Gupta   +5 more
doaj   +1 more source

Candidate Right Locus Coeruleus‐Centered Symptom Pathways in Young Major Depressive Disorder: A Multimodal Magnetic Resonance Imaging Study

Human Brain Mapping, Volume 47, Issue 12, August 15, 2026.
In young major depressive disorder, substantia nigra and locus coeruleus qMRI phenotypes were linked to functional network organization and depressive severity through right locus coeruleus‐centered connectivity pathways. ABSTRACT Major depressive disorder (MDD) involves network‐level abnormalities that may reflect dysfunction in catecholaminergic ...
Zesong Yuan, Jing Wang, Danian Li, Baohua Cheng, Yingpeng Kuang, Rongyu Zhang, Nana Luo, Shijun Qiu, Yongsheng Chen, Yujie Liu   +9 more
wiley   +1 more source

Harmonic field extension for QSM with reduced spatial coverage using physics-informed generative adversarial network

NeuroImage
Quantitative susceptibility mapping (QSM) is frequently employed in investigating brain iron related to brain development and diseases within deep gray matter (DGM). Nonetheless, the acquisition of whole-brain QSM data is time-intensive.
Siyun Jung, Soohyun Jeon, Sung-Min Gho, Ho-Joon Lee, Kyu-Jin Jung, Dong-Hyun Kim   +5 more
doaj   +1 more source

Flexible intervention workflow for MRI guided robotic prostate seed brachytherapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Low‐dose‐rate prostate seed brachytherapy (BT) is an established guideline‐conformal treatment option for low‐risk prostate cancer. Precise seed placement is essential for achieving adequate dose coverage while minimizing exposure of surrounding healthy tissue.
Philipp Aumueller, Mirjam L. Dannert, Martin Polednik, Frank A. Giordano, Jens Fleckenstein, Sven Clausen   +5 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1686-1696, August 2026.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Ex-vivo quantitative susceptibility mapping of human brain hemispheres.

PLoS ONE, 2017
Ex-vivo brain quantitative susceptibility mapping (QSM) allows investigation of brain characteristics at essentially the same point in time as histopathologic examination, and therefore has the potential to become an important tool for determining the ...
Arnold M Evia, Aikaterini Kotrotsou, Ashish A Tamhane, Robert J Dawe, Alifiya Kapasi, Sue E Leurgans, Julie A Schneider, David A Bennett, Konstantinos Arfanakis   +8 more
doaj   +1 more source

Early identification of vascular cognitive impairment from a multimodal perspective: a combined diagnosis from targeted cognitive assessments, imaging biomarkers, and molecular fluid biomarkers to ecological behavioral characteristics

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract Vascular cognitive impairment (VCI), the second leading cause of dementia, is characterized by heterogeneous pathophysiology and a potentially reversible early phase, underscoring the need for timely identification. This review synthesizes advances across four complementary domains – targeted cognitive assessments, imaging biomarkers ...
Wenqi Song, Xiaoqun Liu, Tianrui Yu, Yuanyuan Xiang, Peijie Fu, Moxin Wu, Xiaoping Yin, Xiaorong Zhang, Zhiying Chen   +8 more
wiley   +1 more source