Results 71 to 80 of about 2,779 (160)

Assessment of Optimal T1/T2‐Weighted Combinations for Myelin Sensitivity: Effects of Echo Time and Exponents

Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3176-3186, June 2026.
ABSTRACT Purpose The aim of this study is to improve the traditional T1‐weighted (T1w) over T2‐weighted (T2w) ratio as a proxy for myelin by investigating the optimal T2w TE and combination of exponent‐weighted T1w and T2w images (T1wx1/T2wx2). Methods T1w and T2w Gradient And Spin Echo (GRASE) data were acquired from 14 volunteers, 6 of whom had a ...
Simone Monachino, Gerhard S. Drenthen, Lis J. M. van den Boogaard, Marcel Breeuwer, Catarina Dinis Fernandes, Oliver H. H. Gerlach, Svitlana Zinger, Jacobus F. A. Jansen   +7 more
wiley   +1 more source

Ultrashort Echo Time Quantitative Susceptibility Source Separation in Musculoskeletal System: A Feasibility Study

Journal of Imaging
This study aims to demonstrate the feasibility of ultrashort echo time (UTE)-based susceptibility source separation for musculoskeletal (MSK) imaging, enabling discrimination between diamagnetic and paramagnetic tissue components, with a particular focus
Sam Sedaghat, Jin Il Park, Eddie Fu, Annette von Drygalski, Yajun Ma, Eric Y. Chang, Jiang Du, Lorenzo Nardo, Hyungseok Jang   +8 more
doaj   +1 more source

Ex-vivo quantitative susceptibility mapping of human brain hemispheres.

PLoS ONE, 2017
Ex-vivo brain quantitative susceptibility mapping (QSM) allows investigation of brain characteristics at essentially the same point in time as histopathologic examination, and therefore has the potential to become an important tool for determining the ...
Arnold M Evia, Aikaterini Kotrotsou, Ashish A Tamhane, Robert J Dawe, Alifiya Kapasi, Sue E Leurgans, Julie A Schneider, David A Bennett, Konstantinos Arfanakis   +8 more
doaj   +1 more source

MRI-Based Quantification of Magnetic Susceptibility in Gel Phantoms: Assessment of Measurement and Calculation Accuracy

Radiology Research and Practice, 2018
The local magnetic field inside and around an object in a magnetic resonance imaging unit depends on the magnetic susceptibility of the object being magnetized, in combination with its geometry/orientation.
Emma Olsson, Ronnie Wirestam, Emelie Lind   +2 more
doaj   +1 more source

Reducing Noise Induced by Cardiac Pulsatility in Brain Maps of R2* and Magnetic Susceptibility Using Tailored k‐space Sampling

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
With linear k‐space sampling trajectories, cardiac pulsation leads to MRI signal instabilities that increase the variability (standard deviation, SD) of R2* and QSM maps across repetitions. Here, we propose alternative trajectories that aim to mitigate the impact of cardiac‐induced noise in brain maps of R2* and QSM.
Quentin Raynaud, Thomas Dardano, Rita Oliveira, Giulia Di Domenicantonio, Tobias Kober, Christopher W. Roy, Ruud B. van Heeswijk, Antoine Lutti   +7 more
wiley   +1 more source

Bidirectional genetic and phenotypic links between smoking and striatal iron content involving dopaminergic and inflammatory pathways

Addiction, Volume 121, Issue 6, Page 1580-1593, June 2026.
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova, Ilaria Iuliani, Sven Bergmann   +2 more
wiley   +1 more source

Ultrashort Echo Time Quantitative Susceptibility Mapping (UTE-QSM) of Highly Concentrated Magnetic Nanoparticles: A Comparison Study about Different Sampling Strategies

Molecules, 2019
The ability to accurately and non-invasively quantify highly concentrated magnetic nanoparticles (MNPs) is desirable for many emerging applications. Ultrashort echo time quantitative susceptibility mapping (UTE-QSM) has demonstrated the capability to ...
Xing Lu, Hyungseok Jang, Yajun Ma, Saeed Jerban, Eric Y. Chang, Jiang Du   +5 more
doaj   +1 more source

Quantitative susceptibility and T1ρ mapping of knee articular cartilage at 3T

Osteoarthritis and Cartilage Open
T1ρ and Quantitative Susceptibility Mapping (QSM) are evolving as substrates for quantifying the progressive nature of knee osteoarthritis. Objective: To evaluate the effects of spin lock time combinations on depth-dependent T1ρ estimation, in adjunct to
Allen A. Champagne, Taylor M. Zuleger, Daniel R. Smith, Alexis B. Slutsky-Ganesh, Shayla M. Warren, Mario E. Ramirez, Lexie M. Sengkhammee, Sagar Mandava, Hongjiang Wei, Davide D. Bardana, Joseph D. Lamplot, Gregory D. Myer, Jed A. Diekfuss   +12 more
doaj   +1 more source

Co‐pathologies and biological processes beyond amyloid‐beta and tau in people with Alzheimer's disease: Evidence from clinical cohort studies

Journal of Internal Medicine, Volume 299, Issue 6, Page 694-710, June 2026.
Abstract Alzheimer's disease (AD) is neuropathologically defined by amyloid‐beta (Aβ) plaques and tau neurofibrillary tangles. However, co‐pathologies and other pathobiological processes are involved in the pathogenesis of AD, contributing to neurodegeneration and clinical symptoms.
Daniel Ferreira, Tomasz Chmiela, Maria Eriksdotter, Clifford R. Jack Jr., Grégoria Kalpouzos, Anna Marseglia, Patrizia Mecocci, Agneta Nordberg, Dorota Religa, Eric Westman   +9 more
wiley   +1 more source

Relationship between tau-PET and quantitative susceptibility mapping in atypical Alzheimer’s disease

Frontiers in Aging Neuroscience
BackgroundIron is an important component in neurofibrillary tangles, is known to co-localize with tangles in Alzheimer’s disease (AD) and can be measured using quantitative susceptibility mapping (QSM).
Neha Singh-Reilly, Ryota Satoh, Jonathan Graff-Radford, Mary M. Machulda, Val J. Lowe, Keith A. Josephs, Jennifer L. Whitwell   +6 more
doaj   +1 more source