Results 141 to 150 of about 21,627 (244)

Effects of Marker Density, Number of Quantitative Trait Loci and Heritability of Trait on Genomic Selection Accuracy

open access: yes, 2017
The success of genomic selection mainly depends on the extent of linkage disequilibrium (LD) between markers and quantitative trait loci (QTL), number of QTL and heritability (h2) of the traits. The extent of LD depends on the genetic structure of the population and marker density.
Alanoshahr, F.   +4 more
openaire   +2 more sources

Geometric Morphometrics Reveal Body Shape Variation in Freshwater Shrimps of the Genus Macrobrachium Lacking a Mandibular Palp (Formerly Pseudopalaemon Sollaud, 1911) (Decapoda: Palaemonidae)

open access: yesActa Zoologica, EarlyView.
ABSTRACT Shape variation in the cephalothorax of Macrobrachium species without mandibular palp using geometric morphometrics was used as a tool to support species differentiation and propose new diagnostic characters for taxonomic identification.
Thaís Arrais Mota   +4 more
wiley   +1 more source

Laypeople's Views on the Narrative Identity and Societal Treatment of Genetically Modified People

open access: yesBioethics, EarlyView.
ABSTRACT Genome editing in human embryos could raise new ethical issues by changing future people's narrative and numerical identity. Most philosophers agree that some genetic modifications would have larger effects on identity than others, but they disagree on what criteria might explain these differences and have not supported their claims ...
Derek So, Yann Joly, Robert Sladek
wiley   +1 more source

Novel Perspective of Hormesis in Evolution. [PDF]

open access: yesBiology (Basel)
Vargas-Hernandez M   +7 more
europepmc   +1 more source

A century of theories of balancing selection

open access: yesBiological Reviews, EarlyView.
ABSTRACT Traits that affect organismal fitness are often highly genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature – after all – ‘selects’ the best genotypes at the expense of those that fall short.
Filip Ruzicka   +10 more
wiley   +1 more source

Evolvability: progress and key questions. [PDF]

open access: yesBioscience
Pélabon C   +25 more
europepmc   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning   +19 more
wiley   +1 more source

Expansion of the Phenotypic and Genotypic Spectrum for PRKAR1B‐Related Marbach–Schaaf Neurodevelopmental Syndrome: A Case Series

open access: yesClinical Genetics, EarlyView.
Comprehensive clinical description of 12 subjects with pathogenic PRKAR1B variants, including two heterozygous deletions supporting haploinsufficiency as a possible mechanism of disease, providing valuable insight into the pathophysiology of MASNS and setting a framework upon which to design future mechanistic studies of PKA signaling in brain ...
Sebastian Burkart   +17 more
wiley   +1 more source

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