Results 121 to 130 of about 83,180 (256)

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Sequelae of child maltreatment: Umbrella synthesis of 148 meta‐analyses on the mental health correlates

JCPP Advances, EarlyView.
Our umbrella synthesis found strong, often equivalent, associations between child maltreatment and all examined mental health difficulties. Different types of maltreatment appear to have comparably negative effects on mental health. If replicated, these findings may cause us to reconsider conventional wisdom that suggests some forms of CM are less ...
Barry Coughlan, Robbie Duschinsky, Marian J. Bakermans‐Kranenburg, Lianne Bakkum, Guy C. M. Skinner, Alfred Markham, Helen Beckwith, Marinus H. van Ijzendoorn   +7 more
wiley   +1 more source

Genetic mapping of quantitative trait loci associated with nematode resistance in melon using genotyping-by-sequencing. [PDF]

Front Plant Sci
Sharma M, Kaur A, Bhatia SK, Sharma SP, Kaur S, Narang D, Leela NC, Kumari N, Sarao NK.   +8 more
europepmc   +1 more source

Automated Profiling of Social Behaviors to Assess the Genetic Basis of Evolution of Aggressive Behaviors in Astyanax mexicanus

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Across the animal kingdom, social behaviors such as aggression are critical for survival and reproductive success. While there is significant variation in social behaviors within and between species, the genetic mechanisms underlying natural variation in social behaviors are poorly understood.
Renee Mapa, Stefan Choy, Solomia Lapko, Allison Kimmel, Isabel Carino‐Bazan, Johanna E. Kowalko   +5 more
wiley   +1 more source

Erratum: Expanded methylome and quantitative trait loci detection by long-read profiling of personal DNA. [PDF]

Genome Res
Groza C, Ge B, Cheung WA, Pastinen T, Bourque G.   +4 more
europepmc   +1 more source

Soybean seed coat properties as determinants of natto and sprout quality

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Improving breeding efficiency for superior soybean (Glycine max (L.) Merr.) germplasm used in natto and sprouts requires understanding how seed coat properties relate to quality and functional traits. METHODS We measured seed weight, water uptake, and sprout length and thickness across various genotypes tested at different locations
Mehri Hadinezhad, Simon Lackey, Keith Hubbard, Makayla Giles, Elroy R. Cober   +4 more
wiley   +1 more source

Composite selection signal analysis: Uncovering candidate genes and quantitative trait loci in Indian sheep breeds. [PDF]

PLoS One
Nath S, Illa SK, Worku D, Mukherjee S, Mukherjee A, Yata VK.   +5 more
europepmc   +1 more source

Insect‐resistant soybean genotypes accumulate rutin and its O‐methylated derivative narcissin, a more potent flavonol targeting Anticarsia gemmatalis digestive and detoxification enzymes and reducing larval survival

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Soybean underpins Brazil's agricultural, yet its sustainability is threatened by lepidopteran pests such as Anticarsia gemmatalis. Although insect‐resistant cultivars have long been associated with the constitutive accumulation of quercetin‐derived flavonols, the biochemical mechanisms underlying this resistance remain poorly ...
Jessica Nunes de Assis, Valquira Joana Medina Pinheiro, Jodieh Oliveira Santana Varejão, Ian de Paula Alves Pinto, André Luiz Lourenção, Nathália Silva Oliveira, Giovanna Cassia Mendes Moraes, Eduardo Vinícius Vieira Varejão, Maria Goreti de Almeida Oliveira, Humberto Josué de Oliveira Ramos   +9 more
wiley   +1 more source

An Integrative Genetic Strategy for Identifying Causal Genes at Quantitative Trait Loci in Chickens. [PDF]

Animals (Basel)
Ishikawa A.
europepmc   +1 more source

Gene expression and metabolic variability in fungus‐resistant PIWI (‘Pilzwiderstandsfähig’) grape cultivars

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Fungus‐resistant PIWI (Pilzwiderstandsfähig) grape cultivars are promising for reducing pesticide inputs in viticulture, but their enological potential is still poorly characterized. We performed a pilot, single‐vintage study integrating berry gene expression and phenolic composition in five Italian red PIWI cultivars (Cabernet ...
Villano Clizia, Luciano Alessandra, Carputo Domenico, Frusciante Luigi, Forino Martino, Napolitano Felice, Smimmo Roberta, Gambuti Angelita, Aversano Riccardo   +8 more
wiley   +1 more source