Results 121 to 130 of about 3,726,731 (344)

A comparison of population types used for QTL mapping in Arabidopsis thaliana [PDF]

, 2011
In Arabidopsis, a variety of mapping populations have been used for the detection of quantitative trait loci (QTLs) responsible for natural variation.
Willems, W., Nordborg, M., Koornneef, M., Keurentjes, J.J.B., Eeuwijk, F.A., van   +4 more
core   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

A major genetic locus in Trypanosoma brucei is a determinant of host pathology [PDF]

, 2009
The progression and variation of pathology during infections can be due to components from both host or pathogen, and/or the interaction between them. The influence of host genetic variation on disease pathology during infections with trypanosomes has ...
C. Michael R. Turner, Andy Tait, Tait Andy, Liam J Morrison, McLellan Sarah, C Michael R Turner, Annette MacLeod, Liam J. Morrison, Turner, C.M.R., Sweeney Lindsay, MacLeod Annette, Lindsay Sweeney, MacLeod, A., McLellan, S., MacLeod, Annette, Tait, Andy, Morrison, L.J., McLellan, Sarah, Turner, C Michael R, Sweeney, Lindsay, Morrison Liam J., Sweeney, L., Turner C. Michael R., Morrison, Liam J; id_orcid, Tait, A., Sarah McLellan   +25 more
core   +1 more source

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

Advanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong, Boyang Li, Jiahui Xu, Ruonan Lin, Jinghao Pan, Chenlu Fang, Boxiang Zhang, Lucy Yue Lau, Richard J. Aldridge, Elizabeth A. Whitmore, Yi Chen   +10 more
wiley   +1 more source

Determining causality and consequence of expression quantitative trait loci

Human Genetics, 2014
Expression quantitative trait loci (eQTLs) are currently the most abundant and systematically-surveyed class of functional consequence for genetic variation.
A. J. Battle, S. Montgomery
semanticscholar   +1 more source

A population genetics model of marker-assisted selection [PDF]

, 1997
A deterministic two-loci model was developed to predict genetic response to marker-assisted selection (MAS) in one generation and in multiple generations.
Luo, Z. W., Woolliams, J. A., Luo, Z.W., Woolliams, John, Thompson, R.   +4 more
core  

Mapping of multiple quantitative trait loci affecting bovine spongiform encephalopathy

, 2004
A whole-genome scan was conducted to map quantitative trait loci (QTL) for BSE resistance or susceptibility. Cows from four half-sib families were included and 173 microsatellite markers were used to construct a 2835-cM (Kosambi) linkage map covering 29 ...
Haley, Chris S., de Koning, Dirk-Jan, Hernandez Sanchez, Julio, Williams, John L., Zhang, Chi, Wiener, Pamela   +5 more
core   +1 more source

Genetic mapping of natural variation in potassium concentrations in shoots of Arabidopsis thaliana [PDF]

, 2006
Naturally-occurring variation in K+ concentrations between plant genotypes is potentially exploitable in a number of ways, including altering the relationship between K+ accumulation and growth, enhancing salinity resistance, or improving forage quality.
Leigh, R., Harada, H.
core   +1 more source

TED1 Promotes the Assembly of SCFD3‐D14‐D53 to Reinforce Strigolactone Signaling in Rice

Advanced Science, EarlyView.
This study identifies TED1 as a positive regulator of strigolactones (SL) signaling in rice. The ted1 mutants display dwarfism and increased tillering with significantly reduced SLs sensitivity. Through its longer C‐terminal region, TED1 interacts with D53 and D14 to promote the assembly of SCFD3‐D14‐D53, thereby facilitating the efficient ...
Sheng Luo, Chuanyin Wu, Miao Feng, Wenfan Luo, Rong Miao, Jinsheng Qian, Fan Wang, Chunlei Zhou, Bojuan Liu, Jiale Shao, Ziqi Xun, Yehui Xiong, Zhichao Zhao, Cailin Lei, Shanshan Zhu, Yulong Ren, Xin Wang, Xiuping Guo, Haiyang Wang, Zichao Li, Zhijun Cheng, Qibing Lin, Jianmin Wan   +22 more
wiley   +1 more source

Confirmation of quantitative trait loci affecting fatness in chickens

Genetics Selection Evolution, 2005
In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27.
Poel Jan, Crooijmans Richard MPA, Vereijken Addie LJ, Bovenhuis Henk, Jennen Danyel GJ, Groenen Martien AM   +5 more
doaj   +1 more source