Results 291 to 300 of about 3,726,731 (344)

Analysis of Quantitative Trait Loci.

Methods in molecular biology, 2017
Although the term quantitative trait locus (QTL) strictly refers merely to a genetic variant that causes changes in a quantitative phenotype such as height, QTL analysis more usually describes techniques used to study oligogenic or polygenic traits where each identified locus contributes a relatively small amount to the genetic determination of the ...
D. Duffy
semanticscholar   +6 more sources

Molecular quantitative trait loci

Nature Reviews Methods Primers, 2023
F. Aguet   +6 more
semanticscholar   +3 more sources

Mapping of Quantitative Trait Loci

, 2015
The genomic region associated with the expression of a quantitative trait is referred to as quantitative trait locus (QTL), which may contain one or more genes. QTLs have been grouped into different categories on the basis of their effect size, the effect of environment on their expression, and the manner of their action. QTL mapping is generally based
B. Singh, A. K. Singh
semanticscholar   +2 more sources

Quantitative trait loci and psychopharmacology

Journal of Psychopharmacology, 1991
Unlike simple Mendelian characteristics, individual differences in behavior, including behavioral responses to drugs, are generally distributed continuously, show substantial non-genetic as well as genetic influence, and appear to be influenced by many genes rather than one or two major genes.
Plomin, R, McClearn, G E, Gora-Maslak, G
openaire   +3 more sources

Parameters of Quantitative Trait Loci

Critical Reviews™ in Eukaryotic Gene Expression, 2007
Most traits of medical relevance follow quantitative inheritance patterns. The genetic dissection of quantitative traits poses special challenges for geneticists mainly because of low penetrance and gene-gene and gene-environment interactions. Emerging genome resources and technologies are enabling systematic investigation of the genetic architecture ...
Jian, Yan, Weikuan, Gu
openaire   +2 more sources

Quantitative Trait Loci Mapping

2008
This chapter presents current methods for mapping quantitative trait loci (QTLs) in natural populations especially in humans. We discussed the experimental designs for QTL mapping, traditional methods adopted such as linkage mapping approaches and methods for linkage disequilibrium (LD) mapping.
Dong-Hai, Xiong   +9 more
openaire   +2 more sources

Quantitative trait loci for baseline erythroid traits

Mammalian Genome, 2006
A substantial genetic contribution underlies variation in baseline peripheral blood counts. We performed quantitative trait locus/loci (QTL) analyses to identify chromosome (Chr) regions harboring genes influencing the baseline erythroid parameters in F2 intercrosses between NZW/LacJ, SM/J, and C57BLKS/J inbred mice.
Peters, L L   +5 more
openaire   +2 more sources

Quantitative trait loci for behavioural traits in chickens

Livestock Production Science, 2005
Abstract The detection of quantitative trait loci (QTL) of behavioural traits has mainly been focussed on mouse and rat. With the rapid development of molecular genetics and the statistical tools, QTL mapping for behavioural traits in farm animals is developing.
Buitenhuis, A.J.   +9 more
openaire   +3 more sources

Quantitative trait loci in Drosophila

Nature Reviews Genetics, 2001
Phenotypic variation for quantitative traits results from the simultaneous segregation of alleles at multiple quantitative trait loci. Understanding the genetic architecture of quantitative traits begins with mapping quantitative trait loci to broad genomic regions and ends with the molecular definition of quantitative trait loci alleles. This has been
openaire   +2 more sources

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