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Quantitative Trait Loci (QTL) Mapping

2019
Quantitative trait loci (QTL) are genetic regions that influence phenotypic variation of a complex trait, often through genetic interactions with each other and the environment. These are commonly identified through a statistical genetic analysis known as QTL mapping. Here, I present a step-by-step, practical approach to QTL mapping along with a sample
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Estimation of the contribution of quantitative trait loci (QTL) to the variance of a quantitative trait by means of genetic markers

Theoretical and Applied Genetics, 1996
The estimation of the contribution of an individual quantitative trait locus (QTL) to the variance of a quantitative trait is considered in the framework of an analysis of variance (ANOVA). ANOVA mean squares expectations which are appropriate to the specific case of QTL mapping experiments are derived.
Charcosset, Alain, Gallais, A.
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Educational Software for Mapping Quantitative Trait Loci (QTL)

Journal of Natural Resources and Life Sciences Education, 2007
This educational software was developed to aid teachers and students in their understanding of how the process of identifying the most likely quantitative trait loci (QTL) position is determined between two flanking DNA markers. The objective of the software that we developed was to: (1) show how a QTL is mapped to a position on a chromosome using a ...
T. C. Helms, C. Doetkott
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Identification of Quantitative Trait Loci (QTLs) for Fruit Quality Traits in Apple

Plant Molecular Biology Reporter, 2013
A segregating mapping population of “Co-op 17” × “Co-op 16” was used to identify quantitative trait loci (QTLs) associated with various fruit quality traits in apple. Phenotypic data were collected over 2 years for fruit circumference (in centimeter), diameter at midpoint (in centimeter), length (in centimeter), weight (in gram), total soluble solids ...
Sarah M. Potts   +4 more
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Investigating temperament traits in cattle for quantitative trait loci (QTL) identification

Proceedings of the British Society of Animal Science, 2002
Farm animals show individual variation in their behavioural responses to handling and management systems on farms. These behavioural responses are presumed to reflect underlying temperament traits such as fear or aggression. Information about the location of genes that influence temperament traits could be used in selective breeding programmes to ...
N. Ball   +3 more
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Mapping epigenetic quantitative trait loci (QTL) altering a developmental trajectory

Genome, 2002
Genetic variation in a quantitative trait that changes with age is important to both evolutionary biologists and breeders. A traditional analysis of the dynamics of genetic variation is based on the genetic variance–covariance matrix among different ages estimated from a quantitative genetic model.
Rongling, Wu   +3 more
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Provisional Quantitative Trait Loci (QTL) for the Aschoff Effect in RI Mice

Physiology & Behavior, 1998
Mice of the CXB recombinant inbred (RI) panel were phenotyped for period of locomotor activity in continuous dark (tau) and in continuous 10-lux light (tauLL). There were significant differences in the effect of light on period, delta tau (tauLL-tau), among CXB RI strains and their progenitors.
J R, Hofstetter, A R, Mayeda
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Quantitative trait loci (QTL) for circadian rhythms of locomotor activity in mice

Behavior Genetics, 1995
The locomotor activity of male mice (Mus musculus) was monitored by infrared photo-electric beams under three lighting regimens: LD (12 h of light and 12 h of dark), DD (constant dark), and LL (constant broad-spectrum light, 10 lux). Circadian period of locomotor activity (tau) was compared among 3 inbred strains of mice, C57BL/6J (B6), BALB/c (C), and
J R, Hofstetter   +3 more
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Yield-enhancing quantitative trait loci (QTLs) from wild species

Biotechnology Advances, 2008
Wild species of crop plants are increasingly being used to improve various agronomic traits including yield in cultivars. Dense molecular maps have enabled mapping of quantitative trait loci (QTLs) for complex traits such as yield. QTLs for increased yield have been identified from wild relatives of several crop plants.
B P Mallikarjuna, Swamy, N, Sarla
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Quantitative trait loci (QTL) analysis in a Meishan×Göttingen cross population

Animal Genetics, 2000
In order to locate the genetic regions in the swine genome that are responsible for economically important traits, a resource population has been constructed by mating two female Meishan pigs with a male Göttingen miniature pig. In subsequent generations, 265 F2 offspring were produced from two F1 males and 19 F1 females.
Y Wada   +19 more
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