Results 101 to 110 of about 185,736 (294)

Quantitative trait loci conferring grain mineral nutrient concentrations in durum wheat 3 wild emmer wheat RIL population [PDF]

open access: yes, 2009
Mineral nutrient malnutrition, and particularly deficiency in zinc and iron, afflicts over 3 billion people worldwide. Wild emmer wheat, Triticum turgidum ssp. dicoccoides, genepool harbors a rich allelic repertoire for mineral nutrients in the grain.
A Blanco   +81 more
core   +1 more source

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

open access: yesAdvanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li   +9 more
wiley   +1 more source

Computing power of quantitative trait locus association mapping for haploid loci

open access: yesBMC Bioinformatics, 2009
Background Statistical power calculations are a critical part of any study design for gene mapping. Most calculations assume that the locus of interest is biallelic.
Gordon Derek, Zinn Andrew R
doaj   +1 more source

DSG2+ Cancer Stem Cells Co‐Located With FAP+ Myofibroblasts in the Tumor Boundary That Determines the Efficacy of Immunotherapy in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Cancer stem cells (CSCs) in non‐small cell lung cancer display pronounced plasticity and spatial heterogeneity. By integrating single‐cell and spatial transcriptomics, this study defines a DSG2‐associated CSC program and reveals a tumor‐margin niche formed with FAP+ myofibroblasts.
Guangyu Fan   +8 more
wiley   +1 more source

Placental expression quantitative trait loci in an East Asian population

open access: yesHGG Advances
Summary: Expression quantitative trait loci (eQTL) analysis measures the contribution of genetic variation in gene expression on complex traits. Although this methodology has been used to examine gene regulation in numerous human tissues, eQTL research ...
Jaeyong Choi   +12 more
doaj   +1 more source

Semiparametric Quantitative-Trait-Locus Mapping: II. on Censored Age-at-Onset [PDF]

open access: yes, 2004
In genetic studies, the variation in genotypes may not only affect different inheritance patterns in qualitative traits, but may also affect the age-at-onset as quantitative trait.
Chen, Ying Qing   +2 more
core   +1 more source

Quantitative trait locus analysis.

open access: yesAlcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 2001
Alcoholism is a quantitative disorder that is caused by the combined influences of numerous genes (i.e., quantitative trait loci [QTLs]) and environmental factors. To identify QTLs for alcoholism, researchers compare subject groups (e.g., inbred mouse strains) that differ in both their genetic makeup (i.e., genotype) and alcohol-related trait (e.g ...
openaire   +1 more source

R/qtlcharts: Interactive Graphics for Quantitative Trait Locus Mapping [PDF]

open access: yesGenetics, 2014
Abstract Every data visualization can be improved with some level of interactivity. Interactive graphics hold particular promise for the exploration of high-dimensional data. R/qtlcharts is an R package to create interactive graphics for experiments to map quantitative trait loci (QTL) (genetic loci that influence quantitative traits).
openaire   +3 more sources

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

open access: yesAdvanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos   +12 more
wiley   +1 more source

Foraging environment determines the genetic architecture and evolutionary potential of trophic morphology in cichlid fishes [PDF]

open access: yes, 2016
Phenotypic plasticity allows organisms to change their phenotype in response to shifts in the environment. While a central topic in current discussions of evolutionary potential, a comprehensive understanding of the genetic underpinnings of plasticity is
Albertson, R. Craig   +7 more
core   +2 more sources

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