Results 41 to 50 of about 185,736 (294)

Developmental dyslexia: Genetic dissection of a complex cognitive trait [PDF]

open access: yes, 2002
Developmental dyslexia, a specific impairment of reading ability despite adequate intelligence and educational opportunity, is one of the most frequent childhood disorders.
DeFries, J., Fisher, S.
core   +2 more sources

Bayesian Quantitative Trait Locus Mapping Using Inferred Haplotypes [PDF]

open access: yesGenetics, 2010
Abstract We describe a fast hierarchical Bayesian method for mapping quantitative trait loci by haplotype-based association, applicable when haplotypes are not observed directly but are inferred from multiple marker genotypes. The method avoids the use of a Monte Carlo Markov chain by employing priors for which the likelihood factorizes ...
Durrant, C, Mott, R
openaire   +3 more sources

Development of a Next-Generation NIL Library in Arabidopsis Thaliana for Dissecting Complex Traits [PDF]

open access: yes, 2013
The identification of the loci and specific alleles underlying variation in quantitative traits is an important goal for evolutionary biologists and breeders.
Bauerle, William L.   +8 more
core   +3 more sources

Detection of QTLs controlling heading date in the process of rice development at two environments

open access: yes浙江大学学报. 农业与生命科学版, 2002
Heading date (HD) is a major determinant of the regional and seasonal adaptation of rice varieties. In order to elucidate the quantitative trait loci (QTL) for HD in the process of rice development, a doubled haploid (DH) population was employed to map ...
BAO Jin-song   +3 more
doaj   +1 more source

Threshold and power for Quantitative Trait Locus detection [PDF]

open access: yes, 2010
We propose several new methods to calculate threshold and power for Quantitative Trait Locus (QTL) detection. They are based on asymptotic theoretical results presented in Rabier et al. (2009) . The asymptotic validity is checked by simulations.
Azaïs, Jean-Marc   +3 more
core   +1 more source

Near-periodic substitution and the genetic variance induced by environmental change [PDF]

open access: yes, 2006
We investigate a model that describes the evolution of a diploid sexual population in a changing environment. Individuals have discrete generations and are subject to selection on the phenotypic value of a quantitative trait, which is controlled by a ...
Barton   +29 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Population Genetic Signature of Polygenic Local Adaptation [PDF]

open access: yes, 2014
Adaptation in response to selection on polygenic phenotypes may occur via subtle allele frequencies shifts at many loci. Current population genomic techniques are not well posed to identify such signals.
Berg, Jeremy J., Coop, Graham
core   +8 more sources

Mapping resistant QTLs for rice sheath blight disease with a doubled haploid population

open access: yesJournal of Integrative Agriculture, 2015
Sheath blight (SB) disease, caused by Rhizoctonia solani Kühn, is one of the most serious diseases causing rice (Oryza sativa L.) yield loss worldwide. A doubled haploid (DH) population was constructed from a cross between a japonica variety CJ06 and an ...
Yu-xiang ZENG   +6 more
doaj   +1 more source

Genetic structure and molecular mechanism underlying the stalk lodging traits in maize (Zea mays L.)

open access: yesComputational and Structural Biotechnology Journal, 2023
Stalk lodging seriously affects yield and quality of crops, and it can be caused by several factors, such as environments, developmental stages, and internal chemical components of plant stalks.
Shuai Wang   +6 more
doaj   +1 more source

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