Results 41 to 50 of about 361,741 (406)

Block network mapping approach to quantitative trait locus analysis [PDF]

, 2016
BACKGROUND: Advances in experimental biology have enabled the collection of enormous troves of data on genomic variation in living organisms. The interpretation of this data to extract actionable information is one of the keys to developing novel ...
Daniel M. Gatti, Vipul Periwal, Zeina Z. Shreif   +2 more
core   +2 more sources

krn1, a major quantitative trait locus for kernel row number in maize.

New Phytologist, 2019
Kernel row number is a fundamental component of maize (Zea mays) yield and an important target for maize breeding. The revolutionary transition from the two-rowed teosinte to maize with increased kernel row numbers dramatically enhanced yields during ...
Jian Wang, Zhelong Lin, Xuan Zhang, Hangqin Liu, Leina Zhou, Shuyang Zhong, Yan Li, Can Zhu, Zhongwei Lin   +8 more
semanticscholar   +1 more source

On the Fourier transform of a quantitative trait: Implications for compressive sensing [PDF]

Journal of Theoretical Biology, Vol. 540, Year 2022, Article ID 110985, ISSN 0022-5193, 2021
This paper explores the genotype-phenotype relationship. It outlines conditions under which the dependence of a quantitative trait on the genome might be predictable, based on measurement of a limited subset of genotypes. It uses the theory of real-valued Boolean functions in a systematic way to translate trait data into the Fourier domain.
arxiv   +1 more source

Increased pericarp cell length underlies a major quantitative trait locus for grain weight in hexaploid wheat.

New Phytologist, 2017
Crop yields must increase to address food insecurity. Grain weight, determined by grain length and width, is an important yield component, but our understanding of the underlying genes and mechanisms is limited.
J. Brinton, J. Simmonds, Francesca Minter, M. Leverington-Waite, J. Snape, C. Uauy   +5 more
semanticscholar   +1 more source

Identifying QTLs Related to Grain Filling Using a Doubled Haploid Rice (Oryza sativa L.) Population

Agronomy, 2023
Grain filling is an important trait of rice that affects the yield of grain-oriented crop species with sink capacity-related traits. Here, we used a doubled haploid (DH) population derived from a cross between 93-11 (P1, indica) and Milyang352 (P2 ...
So-Myeong Lee, Nkulu Rolly Kabange, Ju-Won Kang, Youngho Kwon, Jin-Kyung Cha, Hyeonjin Park, Ki-Won Oh, Jeonghwan Seo, Hee-Jong Koh, Jong-Hee Lee   +9 more
doaj   +1 more source

Comparison between instrumental variable and mediation-based methods for reconstructing causal gene networks in yeast [PDF]

Molecular Omics, 2021,17, 241-251, 2020
Causal gene networks model the flow of information within a cell, but reconstructing them from omics data is challenging because correlation does not imply causation. Combining genomics and transcriptomics data from a segregating population allows to orient the direction of causality between gene expression traits using genomic variants.
arxiv   +1 more source

A hierarchical Bayesian approach to multi-trait clinical quantitative trait locus modeling

Frontiers in Genetics, 2012
Recent advances in high-throughput genotyping and transcript profiling technologies have enabled the inexpensive production of genome-wide dense marker maps in tandem with huge amounts of expression profiles.
Crispin M. Mutshinda, Nelly eNoykova, Mikko J. Sillanpää, Mikko J. Sillanpää   +3 more
doaj   +1 more source

Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator

Nature Communications, 2017
Thousands of genetic variants have been associated with complex traits through genome-wide association studies. However, the functional variants or mechanistic consequences remain elusive. Intermediate traits such as gene expression or protein levels are
J. Carayol, C. Chabert, Alessandro Di Cara, C. Armenise, Gregory Lefebvre, D. Langin, N. Viguerie, S. Métairon, W. Saris, A. Astrup, P. Descombes, A. Valsesia, J. Hager   +12 more
semanticscholar   +1 more source

Detection of quantitative trait loci for reproduction and production traits in Large White and French Landrace pig populations (Open Access publication)

Genetics Selection Evolution, 2008
A genome-wide scan was performed in Large White and French Landrace pig populations in order to identify QTL affecting reproduction and production traits.
Bidanel Jean-Pierre, Mercat Marie-José, Ronan Gueblez, Juliette Riquet, Gilbert Hélène, Druet Tom, Iannuccelli Nathalie, Tribout Thierry, Milan Denis, Le Roy Pascale   +9 more
doaj   +1 more source

Bayesian Method for Disease QTL Detection and Mapping, using a Case and Control Design and DNA Pooling [PDF]

Biostatistics (2007) 8:546--565, 2005
This paper describes a Bayesian statistical method for determining the genetic basis of a complex genetic trait. The method uses a sample of unrelated individuals classified into two groups, for example cases and controls. Each group is assumed to have been genotyped at a battery of marker loci using a laboratory effort efficient technique called DNA ...
arxiv   +1 more source