Results 171 to 180 of about 3,533,939 (302)

Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations

Angewandte Chemie, EarlyView.
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach, Ioanna Tsiara, Wawrzyniec Haberek, Weifeng Lin, Daniel Globisch   +4 more
wiley   +2 more sources

Simulation-guided design of peptide-metal coordination interfaces for next-generation metallo-immunotherapy. [PDF]

Nano Converg
Jang Y, Bellier N, Canlas KKV, Lee JY, Kim Y, Park H, Moon JJ.   +6 more
europepmc   +1 more source

Bottom‐Up Coacervate‐Based Artificial Cells: Integrating Cellular Hallmarks into Complex Life‐Like Systems

Angewandte Chemie, EarlyView.
Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo, Angshuman Das, Madelief A. M. Verwiel, Jan C. M. van Hest   +3 more
wiley   +2 more sources

Multiple Application Strategies of Carbon Dots in Cancer Treatment: Mechanisms, Progress and Challenges. [PDF]

Int J Nanomedicine
E K, Luo Y, Wang X, Liu R, Tao H, Zhang J, Han Q, Song Y, Wang G.   +8 more
europepmc   +1 more source

Local Chemical Gradients in a Mammalian Cortex Measured In Vivo With a Silicon Nanodialysis Mass Spectrometry Platform

Angewandte Chemie, EarlyView.
Fluorescence image of the coronal slice of mouse brain where multiple neurochemicals have been measured in vivo with a nanodialysis platform coupled to CE‐MS to reveal strong millimeter‐scale spatial chemical gradients. Formation and maintenance of such local chemical compartments in the otherwise diffusion‐homogeneous cortex indicates strong ...
Weihua Shi, Keyin Li, Yu Ding, Alex G. Armstrong, Jonathan V. Sweedler, Yurii Vlasov   +5 more
wiley   +2 more sources

Quantum Osteoimmunology: A Paradigm Shift in Understanding and Influencing Bone-Immune Crosstalk. [PDF]

ChemMedChem
Li RW, Alzaanin S, Yin Z, Smith PN.
europepmc   +1 more source

Synthetic O‐Polysaccharide Backbone Units for a Single Antigen Vaccine Against Two Major Non‐Typhoidal Salmonella Serovars

Angewandte Chemie, EarlyView.
A modular strategy was developed to synthesize tri‐, hexa‐, and nona‐saccharides representing repeating units of the conserved O‐polysaccharide backbone of Salmonella. Conjugates of these glycans to bacteriophage Qβ induced strong IgG responses in mice and rabbits. Antibodies elicited recognized native O‐polysaccharides and conferred protection against
Xingling Pan, Changxin Huo, Soham Maity, Herbert Kavunja, Rachel Moszyk, Cameron Talbot, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +2 more sources

Biological Systems Depend on Communication Over Distances: A Review of the Fundamental Mechanisms, Associated challenges, and the Potential Effect of the Constrained Disorder Principle. [PDF]

Acta Biotheor
Ilan Y.
europepmc   +1 more source

Single-Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization. [PDF]

Adv Mater
Wu K, Lu Q, Ren Y, Balasubramanian P, Ebadi Jalal K, Klug H, Klein M, Bohn T, Bopp T, Jelezko F, Wu Y, Weil T.   +11 more
europepmc   +1 more source

Advancements in nanobiosensors for early cancer detection, challenges, treatment, and future prospects: a comprehensive review. [PDF]

Discov Nano
Rajput S, Khandia R, Gaur T, Anant A, Kamal MA, Gurjar P, Al-Hussain SA, Zaki MEA.   +7 more
europepmc   +1 more source