Results 181 to 190 of about 3,533,939 (302)

Toward next-generation machine learning and deep learning for spatial omics. [PDF]

Brief Bioinform
Zirem Y, Fournier I, Salzet M.
europepmc   +1 more source

Cancer in transition: discovery of tumor-intrinsic transcriptional programs shaping the immune and microenvironmental landscape. [PDF]

Biomark Res
Spitschak A, Casalegno Garduño R, Pützer BM.   +2 more
europepmc   +1 more source

Challenges and Advances in Bioinformatics and Computational Biology. [PDF]

Curr Issues Mol Biol
Si T, Gong H.
europepmc   +1 more source

Advancing understanding of long COVID pathophysiology through quantum walk-based network analysis. [PDF]

Bioinform Adv
Park J, Hwang W, Lee S, Lee HC, MacMahon M, Zilbauer M, Han N.   +6 more
europepmc   +1 more source

A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase

Angewandte Chemie International Edition, EarlyView.
The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne, Jonathan Pettinger, Teresa Weckwerth, Andrew Purkiss, Sing Hei Lok, Louisa Penicaut, Roksana Ogrodowicz, Raveena Prema, Simone Kunzelmann, Chloe Roustan, Ganka Bineva‐Todd, Saskia Pieters, Francesca Zappacosta, Alfred E. Doherty, Isobel Oram, Christelle Soudy, Robert Quinlan, Joanna Redmond, Svend Kjaer, David House, Stephane Mouilleron, Jacob T. Bush, Benjamin Schumann   +22 more
wiley   +1 more source

Incorporation of Novel Synthetic Glycolipids in Liposomal Nanoparticles Affects Opsonization and In Vivo Clearance

Angewandte Chemie International Edition, EarlyView.
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu, Xuehan Li, Yu Gao, Shijia Tao, Xiaofei Li, Lemei Zhao, Wenshuai Han, Hao Fan, Ying Qiu, Man Wang, Luying Zhou, Xiaoyan Fang, Wenhua Yang, Haiyang Zhang, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang, Xiangzhao Mao   +18 more
wiley   +1 more source

A quantum-inspired, biomimetic, and fractal framework for self-healing AI code generation: bridging responsible automation and emergent intelligence. [PDF]

Front Artif Intell
Nehzati M.
europepmc   +1 more source

AI-quantum framework for accurate infertility risk classification in PCOS patients using EHR data. [PDF]

Front Artif Intell
Sarath T, Brindha K.
europepmc   +1 more source

Navigating the <i>Nanoverse</i>: how emerging nanomaterials are transforming bioscience and society. [PDF]

Nanoscale Adv
Saorin A, Subrati A, Saorin G, Moscatiello GY, Natale C, Bellido-Peralta R, Cazzador G, Guérin M, Crozzolin M, Vallet-Buisan M, Salmaso A, Punz B, Catalini S, Morelli A, Martinez-Serra A.   +14 more
europepmc   +1 more source

The Recognition of YopJ Family Effectors Depends on ZAR1/JIM2 Immune Complex in Nicotiana benthamiana. [PDF]

Mol Plant Pathol
Kim I, Kim J, Ahn YJ, Sohn KH, Segonzac C.   +4 more
europepmc   +1 more source