Results 71 to 80 of about 463,836 (293)

An Overview of Some Practical Quasi-Newton Methods for Unconstrained Optimization

open access: yesSultan Qaboos University Journal for Science, 2007
Quasi-Newton methods are among the most practical and efficient iterative methods for solving unconstrained minimization problems. In this paper we give an overview of some of these methods with focus primarily on the Hessian approximation updates and ...
M. Al-Baali, H. Khalfan
doaj   +1 more source

Stabilized material point methods for coupled large deformation and fluid flow in porous materials

open access: yes, 2019
The material point method (MPM) has been increasingly used for the simulation of large deformation processes in fluid-infiltrated porous materials. For undrained poromechanical problems, however, standard MPMs are numerically unstable because they use ...
Choo, Jinhyun, Zhao, Yidong
core   +2 more sources

GloPath: An Entity‐Centric Foundation Model for Glomerular Lesion Assessment and Clinicopathological Insights

open access: yesAdvanced Science, EarlyView.
An entity‐centric foundation model, GloPath, is introduced for comprehensive glomerular lesion assessment from routine renal biopsy images. Trained on over one million glomeruli, the framework enables robust lesion recognition, grading, and cross modality diag nosis, while uncovering large‐scale clinicopathological associations.
Qiming He   +28 more
wiley   +1 more source

Identifying and attacking the saddle point problem in high-dimensional non-convex optimization [PDF]

open access: yes, 2014
A central challenge to many fields of science and engineering involves minimizing non-convex error functions over continuous, high dimensional spaces.
Caglar Gulcehre   +6 more
core  

Quasi-Newton methods: superlinear convergence without line searches for self-concordant functions [PDF]

open access: yesOptim. Methods Softw., 2016
We consider the use of a curvature-adaptive step size in gradient-based iterative methods, including quasi-Newton methods, for minimizing self-concordant functions, extending an approach first proposed for Newton's method by Nesterov.
Wenbo Gao, D. Goldfarb
semanticscholar   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

open access: yesAdvanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu   +4 more
wiley   +1 more source

An Approximate Quasi-Newton Bundle-Type Method for Nonsmooth Optimization

open access: yesAbstract and Applied Analysis, 2013
An implementable algorithm for solving a nonsmooth convex optimization problem is proposed by combining Moreau-Yosida regularization and bundle and quasi-Newton ideas. In contrast with quasi-Newton bundle methods of Mifflin et al.
Jie Shen, Li-Ping Pang, Dan Li
doaj   +1 more source

Topology‐Enriched Toughness Enhancement in Quasi‐Periodic Metastructures Featuring Tailorable Strong‐Weak Network

open access: yesAdvanced Science, EarlyView.
A quasi‐periodic Dart‐Kite (QDK) metastructure with a golden‐ratio‐constrained strong–weak bond network simultaneously enhances strength, toughness, and damage tolerance. Its distributed topology enables predictable, tailorable crack paths for precise fracture control and stable mechanics, demonstrating a high‐performance, controllable architecture ...
Tianyu Gao   +3 more
wiley   +1 more source

Scale‐up of Streptomyces species cultivations based on the morphological response to the energy dissipation rate

open access: yesAIChE Journal, EarlyView.
Abstract Filamentous microorganisms exhibit complex morphologies that influence product formation and are affected by various bioprocess parameters. Consistent morphology is therefore essential for comparable results during scale‐up. This study investigates the scale‐up of Streptomyces species (Streptomyces spp.) cultivations from shake flasks to ...
Gesa Brauneck   +12 more
wiley   +1 more source

On Stochastic and Deterministic Quasi-Newton Methods for Nonstrongly Convex Optimization: Asymptotic Convergence and Rate Analysis

open access: yesSIAM Journal on Optimization, 2020
Motivated by applications arising from large-scale optimization and machine learning, we consider stochastic quasi-Newton (SQN) methods for solving unconstrained convex optimization problems.
Farzad Yousefian, A. Nedić, U. Shanbhag
semanticscholar   +1 more source

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