Results 51 to 60 of about 557 (166)

Tricaproin Isolated From Simarouba glauca Inhibits the Growth of Human Colorectal Carcinoma Cell Lines by Targeting Class-1 Histone Deacetylases

Frontiers in Pharmacology, 2018
While anticancer properties of Simarouba glauca (SG, commonly known as Paradise tree) are well documented in ancient literature, the underlying mechanisms leading to cancer cell death begin to emerge very recently.
Asha Jose, Motamari V. N. L. Chaitanya, Elango Kannan, SubbaRao V. Madhunapantula   +3 more
doaj   +1 more source

Bruceae Fructus Oil Inhibits Triple-Negative Breast Cancer by Restraining Autophagy: Dependence on the Gut Microbiota-Mediated Amino Acid Regulation

Frontiers in Pharmacology, 2021
Triple-negative breast cancer (TNBC) has been acknowledged as an aggressive disease with worst prognosis, which requires endeavor to develop novel therapeutic agents. Bruceae fructus oil (BO), a vegetable oil derived from the fruit of Brucea javanica (L.)
Jiyan Su, Xiaohong Chen, Xiaohong Chen, Yuanjie Xiao, Dan Li, Muxia Li, Hongfu Li, Jiangjian Huang, Zhengquan Lai, Ziren Su, Yizhen Xie, Dajiang Zhu, Qianjun Chen, Hai Lu, Jingjin He, Jingjin He, Chenglai Xia, Chenglai Xia   +17 more
doaj   +1 more source

Decoding the Chloroplast Genome of Bitterwood (Picrasma quassioides): Structure, Variability, and Evolutionary Relationships

Ecology and Evolution, Volume 15, Issue 4, April 2025.
This study reports the complete chloroplast genome of Picrasma quassioides, revealing its quadripartite structure, 132 genes, and insights into the evolution of Simaroubaceae. We identified potential molecular markers for species identification, found evidence of selective pressures, and established a robust phylogenetic framework, thereby providing ...
Qin Liu, Huaxi Huang, Jinhang Lin, Fanglin Liu, Xuexue Wang, Rong Chen, Xiaoshan Geng   +6 more
wiley   +1 more source

Physicochemical Effects of the Major Quassinoids in a Standardized Extract (Fr 2) on the Bioavailability and Pharmacokinetic Properties, and their Implications for Oral Antimalarial Activity

Natural Product Communications, 2011
A simple validated LC-UV method for the phytochemical analysis of four bioactive quassinoids, 13α(21)-epoxyeurycomanone ( EP ), eurycomanone ( EN ), 13α,21-dihydroeurycomanone ( ED ) and eurycomanol ( EL ) in rat plasma following oral (200 mg/kg) and ...
Bin-Seng Low, Chin-Hoe Teh, Kah-Hay Yuen, Kit-Lam Chan   +3 more
doaj   +1 more source

Cytotoxic Compounds from Brucea mollis

Scientia Pharmaceutica, 2016
Ten compounds, including soulameanone (1), isobruceine B (2), 9-methoxy-canthin-6-one (3), bruceolline F (4), niloticine (5), octatriacontan-1-ol (6), bombiprenone (7), α-tocopherol (8), inosine (9), and apigenin 7-O-β-D-glucopyranoside (10), were ...
Mai Hung Thanh TUNG, Ho Viet ĐUC, Tran Thu HUONG, Nguyen Thanh DUONG, Do Thi PHUONG, Do Thi THAO, Bui Huu TAI, Young Ho KIM, Tran The BACH, Nguyen Manh CUONG   +9 more
doaj   +1 more source

Efficacy and safety of Brucea javanica oil soft capsules combined with oral chemotherapy for maintenance therapy in advanced gastric cancer

Precision Medical Sciences, Volume 14, Issue 1, Page 41-45, March 2025.
Abstract The objective of this study is to compare the efficacy and safety of Brucea javanica (Yadanzi) oil soft capsules (YDZ capsules) with or without Capecitabine/S‐1 in maintenance therapy for advanced gastric cancer (GC). From January 2019 to December 2021, 105 patients treated at Jiangsu Cancer Hospital were enrolled and categorized into 3 ...
Yingying Kou, Mengting Sun, Bingxun Ling, Xianglei Ma, Wenbo Zhu, Min Zhao   +5 more
wiley   +1 more source

Anti-babesial Quassinoids from the Fruits of

Natural Product Communications, 2008
The medicinal plant Brucea javanica (L.) Merr. (Simaroubaceae), grown in China, was examined for anti-babesial properties. The anti-babesial activity of the fruit was found to be attributed to its quassinoid constituents.
Ahmed Elkhateeb, Masahiro Yamasaki, Yoshimitsu Maede, Ken Katakura, Kensuke Nabeta, Hideyuki Matsuura   +5 more
doaj   +1 more source

Communic Acids: Occurrence, Properties and Use as Chirons for the Synthesis of Bioactive Compounds

Molecules, 2012
Communic acids are diterpenes with labdane skeletons found in many plant species, mainly conifers, predominating in the genus Juniperus (fam. Cupresaceae).
Alejandro F. Arteaga, Pilar Arteaga, Jesús F. Arteaga, Alejandro F. Barrero, M. Mar Herrador   +4 more
doaj   +1 more source

Phytohormones and emerging plant growth regulators in tailoring plant immunity against viral infections

Physiologia Plantarum, Volume 177, Issue 2, March/April 2025.
Abstract Viral infections are major contributors to crop yield loss and represent a significant threat to sustainable agriculture. Plants respond to virus attacks by activating sophisticated signalling cascades that initiate multiple defence mechanisms.
Kritika Shukla, Nikita, Altaf Ahmad, Md Salik Noorani, Ravi Gupta   +4 more
wiley   +1 more source

Antiplasmodial Natural Products

Molecules, 2011
Malaria is a human infectious disease that is caused by four species of Plasmodium. It is responsible for more than 1 million deaths per year. Natural products contain a great variety of chemical structures and have been screened for antiplasmodial ...
Cláudio R. Nogueira, Lucia M. X. Lopes
doaj   +1 more source