Results 91 to 100 of about 555,071 (331)

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Growth and dissection of a fold and thrust belt: the geological record of the High Agri Valley, Italy

open access: yesJournal of Maps, 2020
We present a 130 km2 wide geological map for the NE side of the fault-bounded High Agri Valley Southern Italy, that formed in the Quaternary in response to extensional tectonics dissecting the folds and thrusts of the Lucanian Apennine.
Francesco Bucci   +3 more
doaj   +1 more source

Role of the Subunits Interactions in the Conformational Transitions in Adult Human Hemoglobin: an Explicit Solvent Molecular Dynamics Study

open access: yes, 2012
Hemoglobin exhibits allosteric structural changes upon ligand binding due to the dynamic interactions between the ligand binding sites, the amino acids residues and some other solutes present under physiological conditions.
Baldwin J.   +44 more
core   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Antimicrobial Polymeric Materials with Quaternary Ammonium and Phosphonium Salts

open access: yesInternational Journal of Molecular Sciences, 2015
Polymeric materials containing quaternary ammonium and/or phosphonium salts have been extensively studied and applied to a variety of antimicrobial-relevant areas.
Yan Xue, H. Xiao, Yi Zhang
semanticscholar   +1 more source

A review of artificial intelligence in brachytherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen   +4 more
wiley   +1 more source

Geomorphology and dating of the sand ramp (Kouh Rig) in Farashah, Taft, on the purpose of determining the last quaternary features of the northern slopes of Shirkouh [PDF]

open access: yesکاوش‌های جغرافیایی مناطق بیابانی, 2018
The sand ramp (or Kouh Rig as in Farsi) is a phenomenon formed by accumulation of sand and other materials in the upwind side or leeside of a mountain slope.
Morteza Fattahi, Dariush Mehrshahi
doaj   +1 more source

Synthesis of Low Pt-Based Quaternary PtPdRuTe Nanotubes with Optimized Incorporation of Pd for Enhanced Electrocatalytic Activity.

open access: yesJournal of the American Chemical Society, 2017
Improving heteroatomic interactions via alloying or forming heterogeneous catalysts is of importance to the enhancement in terms of electrocatalytic activity and stability.
Si-Yue Ma   +5 more
semanticscholar   +1 more source

Unsupervised non‐small cell lung cancer tumor segmentation using cycled generative adversarial network with similarity‐based discriminator

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Tumor segmentation is crucial for lung disease diagnosis and treatment. Most existing deep learning‐based automatic segmentation methods rely on manually annotated data for network training. Purpose This study aims to develop an unsupervised tumor segmentation network smic‐GAN by using a similarity‐driven generative adversarial ...
Chengyijue Fang   +2 more
wiley   +1 more source

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