Results 81 to 90 of about 12,249 (253)

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration

Angewandte Chemie, EarlyView.
The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti, Hannah Dreisbach, Rémi Corlay, Clara Weber, Tamara Reiter, Wael Elaily, Bastian Daniel, Klaus Zangger, Pedro A. Sánchez‐Murcia, Mélanie Hall   +9 more
wiley   +2 more sources

Effect of aminoacids on the fungicidal activity of quaternary ammonium salts

Acta Mycologica, 2013
Amphipatic compounds exhibit an antimicrobial action both on bacteria and fungi. It is caused by a penetrative property of hydrophobic carbon chain of the compuound into a plasma membrane as well as by additional interaction of membrane elements and a ...
Jerzy Piątkowski, Michał Świątek
doaj   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

Advanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei, Yogambha Ramaswamy, Young Jung No   +2 more
wiley   +1 more source

Synthesis of cyclic tert-amines and their salts based on dimethylaminopropylamine and aminoethylpiperazine and their biological activity

Тонкие химические технологии
Objectives. The work set out to obtain cyclic tert-amines by alkylation of dimethylaminopropylamine (DMAPA) and aminoethylpiperazine (AEP) with cis-1,4-dichloro-2-butene and cis-2,3-di(chloromethyl)-gem-dichlorocyclopropane.
Yu. G. Borisova, N. I. Medvedeva, R. M. Sultanova, G. Z. Raskil’dina, S. S. Zlotskii   +4 more
doaj   +1 more source

Towards an asymmetric β-selective addition of azlactones to allenoates

Beilstein Journal of Organic Chemistry
We herein report the asymmetric organocatalytic addition of azlactones to allenoates. Upon using chiral quaternary ammonium salt catalysts, i.e., Maruoka’s binaphthyl-based spirocyclic ammonium salts, the addition of various azlactones to allenoates ...
Behzad Nasiri, Ghaffar Pasdar, Paul Zebrowski, Katharina Röser, David Naderer, Mario Waser   +5 more
doaj   +1 more source

Ion Transfer During Ionomer Contact Electrification: Binding Affinity Controls Charging

Angewandte Chemie International Edition, EarlyView.
The binding affinity between mobile ions and fixed ionomer groups determines the amount of charge transferred during contact electrification. Ionomers with a series of mobile alkali cations as well as mobile anions establish a clear ordering in charge transfer, where higher interaction strength leads to lower charge transfer.
John R. Hoffman, Stefan A. Freunberger, Scott Waitukaitis   +2 more
wiley   +1 more source

Quaternary Ammonium Salts of Cationic Lipopeptides with Lysine Residues - Synthesis, Antimicrobial, Hemolytic and Cytotoxic Activities. [PDF]

Probiotics Antimicrob Proteins, 2023
Sikora K, Jędrzejczak J, Bauer M, Neubauer D, Jaśkiewicz M, Szaryńska M.   +5 more
europepmc   +1 more source

Advanced Separation Technologies for Light Olefin and Alkane (C2‐C4): Recent Advances in Extraction, Adsorption, and Membrane Separation

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT With the rapid development of the petrochemical industry, efficient separation technology for olefins and alkanes with the same number of carbon atoms has become an important research topic to enhance the efficiency of petroleum resource utilization and optimize product quality.
Shasha Zhao, Kang Zhao, Zhen Liu
wiley   +1 more source

Performance Assessment and Lab‐Scale Economic Evaluation of Alkaline Extraction and Comparative Precipitation of Cyanobacterial Proteins

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Algal proteins from cyanobacteria serve as a natural source of biopolymers. The principal challenge manifests as nonoptimization of unit operations in downstream process accounting for higher costs. This study focuses on process assessment of unit‐operations for selecting suitable recovery strategies not only based on yield, but also considers
Neha Goel, Ariz Hussain, Poonam Choudhary   +2 more
wiley   +1 more source