Results 81 to 90 of about 2,423 (258)

Efficient quaternion CUR method for low-rank approximation to quaternion matrix

Numerical Algorithms
Abstract The low-rank quaternion matrix approximation has been successfully applied in many applications involving signal processing and color image processing. However, the cost of quaternion models for generating low-rank quaternion matrix approximation is sometimes considerable due to the computation of the quaternion singular value ...
Peng-Ling Wu, Kit Ian Kou, Hongmin Cai, Zhaoyuan Yu   +3 more
openaire   +3 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Least Squares Pure Imaginary Solution and Real Solution of the Quaternion Matrix Equation AXB+CXD=E with the Least Norm

Journal of Applied Mathematics, 2014
Using the Kronecker product of matrices, the Moore-Penrose generalized inverse, and the complex representation of quaternion matrices, we derive the expressions of least squares solution with the least norm, least squares pure imaginary solution with the
Shi-Fang Yuan
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Improving the Precision and Speed of Euler Angles Computation from Low-Cost Rotation Sensor Data

Sensors, 2015
This article compares three different algorithms used to compute Euler angles from data obtained by the angular rate sensor (e.g., MEMS gyroscope)—the algorithms based on a rotational matrix, on transforming angular velocity to time derivations of the ...
Aleš Janota, Vojtech Šimák, Dušan Nemec, Jozef Hrbček   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The Real and Complex Hermitian Solutions to a System of Quaternion Matrix Equations with Applications

International Journal of Mathematics and Mathematical Sciences, 2012
We establish necessary and sufficient conditions for the existence of and the expressions for the general real and complex Hermitian solutions to the classical system of quaternion matrix equations A1X=C1,XB1=C2, and  A3XA3*=C3. Moreover, formulas of the
Shao-Wen Yu
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A Global Krylov Subspace Method for the Sylvester Quaternion Matrix Equation

Journal of New Theory
This study concerns the Sylvester matrix equation in the quaternion setting when the coefficient matrices as well as the unknown matrix have quaternion entries.
Sinem Şimşek
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source