Results 81 to 90 of about 93,711 (291)
Advanced Science, EarlyView.This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
Big Data and Cognitive ComputingQuantum key distribution (QKD), a key application of quantum information technology and “one-time pad” (OTP) encryption, enables secure key exchange with information-theoretic security, meaning its security is grounded in the laws of physics rather than ...
Esraa M. Ghourab +2 more
doaj +1 more source
Scalable quantum computing with Josephson charge qubits
, 2003 A goal of quantum information technology is to control the quantum state of a system, including its preparation, manipulation, and measurement. However, scalability to many qubits and controlled connectivity between any selected qubits are two of the ...
D. Deutsch +4 more
core +1 more source
Advanced Science, EarlyView.We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel +16 more
wiley +1 more source
Majorana Superconducting Qubit
Physical Review Letters, 2018 We propose a platform for universal quantum computation that uses conventional $s$-wave superconducting leads to address a topological qubit stored in spatially separated Majorana bound states in a multi-terminal topological superconductor island.
Schrade, Constantin, Fu, Liang
openaire +5 more sources
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Cosmic muon flux attenuation methods for superconducting qubit experiments
New Journal of PhysicsWe propose and demonstrate two practical mitigation methods to attenuate the cosmic muon flux, compatible with experiments involving superconducting qubits: shallow underground sites and device orientation. Using a specifically-built cosmic muon detector,
Elia Bertoldo +5 more
doaj +1 more source
Quantum Natural Language Processing: A Comprehensive Survey
IEEE AccessBy using the quantum mechanics phenomenon, quantum computers provide a new dimension of computational power that drastically accelerates solving complex and resource-intensive problems.
Charles M. Varmantchaonala +3 more
doaj +1 more source
Using hybrid topological-spin qubit systems for two-qubit-spin gates
, 2012 We investigate a hybrid quantum system involving spin qubits, based on the spins of electrons confined in quantum dots, and topological qubits, based on Majorana fermions.
Flensberg, Karsten, Leijnse, Martin
core +1 more source
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source