Results 111 to 120 of about 128,103 (312)

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

Quercetin alleviates inflammation induced by porcine reproductive and respiratory syndrome virus in MARC‐145 cells through the regulation of arachidonic acid and glutamine metabolism

Veterinary Medicine and Science
Background Porcine reproductive and respiratory syndrome virus (PRRSV) infection causes severe inflammatory response, respiratory disease and sow reproductive failure.
Qian Guang, Long‐Ze Zhang, Xin Tang, Jia‐Kai Li, Chong Cao, Hong‐Bo Chen, Long‐Xin Qiu   +6 more
doaj   +1 more source

Drug-Phospholipid Complex-loaded Matrix Film Formulation for the Enhanced Transdermal Delivery of Quercetin [PDF]

, 2018
A novel quercetin-phospholipid-complex (QPLC)-loaded matrix film for improved transdermal delivery of quercetin was developed. QPLC formulation, prepared using a solvent-evaporation method was optimized using a central-composite design.
Milind Umekar, Kuldeep Wavare, Wavare, Kuldeep D., Telange, Darshan R., Patil, Arun T., Vivek Dave, Sridhar Anand, Arun Patil, Dave, Vivek S., Darshan Telange, Umekar, Milind J., Anand, Sridhar   +11 more
core  

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

The Impact of Quercetin- Geniposide Interaction on the Growth and Properties of Quercetin Nanocrystals

Natural Product Communications
Objective: In this study, the impact of geniposide on the growth of quercetin nanowires was systematically investigated. Subsequently, quercetin nanorods with reduced particle size were synthesized.
Wei Lv, Huiwen Zhang, Na Sai, Rongli Li, Jian Li, Ruming Liang, Chunlei Miao, Rui Huangfu, Zhigang Zhang, Jie Wang, Yujun Yao, Guoliang Xing, Shikui Wu   +12 more
doaj   +1 more source

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory, Gonzalo Villapalos Garcia, Dora Koller, Solomon Adams, Chad A. Bousman, Evangelia Eirini Tsermpini, Michelle Whirl‐Carrillo, Amy J. Turner, Volker M. Lauschke, Mohamed Nagy, Erin C. Boone, Teri E. Klein, Pablo Zubiaur, Andrea Gaedigk   +13 more
wiley   +1 more source

Antibacterial properties of quercetin

Microbiology Research, 2017
Quercetin is a polyphenolic flavonoid with potential chemoprotective properties. In the present work its antibacterial properties were studied against Staphylococcus aureus, Escherichia coli, Shigella flexneri, Proteus vulgaris, Pseudomonas aeruginosa, Lactobacillus casei var shirota by broth dilution method. Quercetin inhibited S.
openaire   +3 more sources

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers

The American Journal of Clinical Nutrition, 1995
Quercetin is a dietary antioxidant that prevents oxidation of low-density lipoproteins in vitro. Intake of quercetin was inversely associated with coronary heart disease mortality in elderly Dutch men. However, the extent of absorption of quercetin in humans is unclear.
Hollman, P.C.H., de Vries, J.H.M., van Leeuwen, S.D., Mengelers, M.J.B., Katan, M.B.   +4 more
openaire   +3 more sources

Validation and Application of an HPLC–UV Method for the Quantification of 3‐O‐Methylquercetin in Nasal Mucosa

ELECTROPHORESIS, EarlyView.
This study improved an HPLC–UV method for quantifying 3‐O‐methylquercetin in porcine nasal mucosa following ICH M10 and ANVISA (Brazil) guidelines, assessing selectivity, linearity, accuracy, precision, and robustness. The method was applied for the first time to evaluate release, permeation, and retention profiles of a nasal formulation.
Jeniffer Viviana Ramirez Hernández, Laura da Silva Machado, Flávia Nathiely Silveira Fachel, Sara Elis Bianchi, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +6 more
wiley   +1 more source