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Bioavailability of Quercetin in Humans with a Focus on Interindividual Variation [PDF]
Comprehensive Reviews in Food Science and Food Safety, 2018 A Filipa Almeida +2 more
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Toxicology and Applied Pharmacology, 2007
Free radical scavenging antioxidants, such as quercetin, are chemically converted into oxidation products when they protect against free radicals. The main oxidation product of quercetin, however, displays a high reactivity towards thiols, which can lead to the loss of protein function.
Agnes W, Boots +6 more
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Free radical scavenging antioxidants, such as quercetin, are chemically converted into oxidation products when they protect against free radicals. The main oxidation product of quercetin, however, displays a high reactivity towards thiols, which can lead to the loss of protein function.
Agnes W, Boots +6 more
openaire +2 more sources
Mechanism of antioxidant properties of quercetin and quercetin-DNA complex
Journal of Molecular Modeling, 2020Quercetin is the most abundant flavonoid with potent antioxidant activities. In the current research, the antioxidant properties of quercetin and quercetin-DNA complex were investigated theoretically and experimentally. Free radical scavenging experiments with thiobarbituric acid-reactive substances (TBARS) and 1,1-diphenyl-2-trinitrophenylhydrazine ...
Xiaoli, Song, Yali, Wang, Liguo, Gao
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Quercetin, apoptosis, heat shock
Biochemical Pharmacology, 2002The present study was designed to investigate the correlation between the expression level of Hsp27 and Hsp72 and induction of apoptosis in HeLa cells in response to quercetin treatment. Treatment of HeLa cells with quercetin or with 1hr period of hyperthermia (42 degrees) increased the number of apoptotic cells.
Joanna, Jakubowicz-Gil +2 more
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Quercetin pharmacokinetics in humans
Biopharmaceutics & Drug Disposition, 2008AbstractThe purpose of this study was to examine the pharmacokinetics of quercetin aglycone as well as its conjugated metabolites and to develop a population pharmacokinetic model for quercetin that incorporates enterohepatic recirculation. The stability of quercetin in different matrices at various temperatures and pH, and the quercetin content of six
Young J, Moon +3 more
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Inactivation of quercetin mutagenicity
Food and Chemical Toxicology, 1984Combinations of oxygen and alkaline pH were found to inactivate irreversibly the mutagenicity of quercetin towards Salmonella typhimurium strain TA98. Exposure time, quercetin concentration and polyphenol oxidase were also important variables determining the extent of quercetin inactivation.
M, Friedman, G A, Smith
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Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers
European Journal of Clinical Pharmacology, 2000Quercetin is a flavonoid with a wide range of biological activities. It mainly occurs in plants as glycosides, such as rutin (quercetin rutinoside) in tea. Quercetin and rutin are used in many countries as vasoprotectants and are ingredients of numerous multivitamin preparations and herbal remedies.The primary objective was to characterise and compare ...
I, Erlund +7 more
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Quercetin Metabolites In Plasma of Rats Fed Diets Containing Rutin or Quercetin
The Journal of Nutrition, 1995We studied the bioavailability and the plasma transport of flavonols in rats fed quercetin or rutin diets. Wistar rats were fed one of the following purified diets for 10 d: control; 16.4 or 8.2 mmol rutin/kg diet; or 16.4, 8.2 or 4.1 mmol quercetin/kg diet. Flavonol concentrations were determined in plasma, ileal and cecal contents, and feces. In rats
Manach, Claudine +7 more
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Antioxidant Properties of Quercetin
2011Quercetin, a plant-derived aglycone form of flavonoid glycosides, has been used as a nutritional supplement and may be beneficial against a variety of diseases, including cancer. We examined the antioxidant properties of quercetin. The reduction potential of quercetin was measured at various pH values using voltammetric methods, and its total ...
Mei, Zhang +16 more
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