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Mechanism of antioxidant properties of quercetin and quercetin-DNA complex

Journal of Molecular Modeling, 2020
Quercetin is the most abundant flavonoid with potent antioxidant activities. In the current research, the antioxidant properties of quercetin and quercetin-DNA complex were investigated theoretically and experimentally. Free radical scavenging experiments with thiobarbituric acid-reactive substances (TBARS) and 1,1-diphenyl-2-trinitrophenylhydrazine ...
Xiaoli, Song, Yali, Wang, Liguo, Gao
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Quercetin pharmacokinetics in humans

Biopharmaceutics & Drug Disposition, 2008
AbstractThe purpose of this study was to examine the pharmacokinetics of quercetin aglycone as well as its conjugated metabolites and to develop a population pharmacokinetic model for quercetin that incorporates enterohepatic recirculation. The stability of quercetin in different matrices at various temperatures and pH, and the quercetin content of six
Young J, Moon   +3 more
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Inactivation of quercetin mutagenicity

Food and Chemical Toxicology, 1984
Combinations of oxygen and alkaline pH were found to inactivate irreversibly the mutagenicity of quercetin towards Salmonella typhimurium strain TA98. Exposure time, quercetin concentration and polyphenol oxidase were also important variables determining the extent of quercetin inactivation.
M, Friedman, G A, Smith
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Quercetin and the mutagenicity of wines

Mutagenesis, 1993
Various studies have shown the mutagenicity of red wine. The major mutagens identified in red wine have been flavonoids, i.e. rutin and its aglycone quercetin. Besides flavonoids, however, it has recently been reported that H2O2 may account for the mutagenicity of red wine in the L-Arabinose resistance test.
J, Gaspar   +5 more
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The Preparation and Analysis of Quercetin

Journal of the American Pharmaceutical Association (Scientific ed.), 1953
Quercetin (3, 3′, 4′, 5, 7-pentahydroxyflavone ) was prepared by hydrolysis with dilute acids of the naturally occurring glycosides, rutin and quercitrin. Data were ogtained on the rate of hydrolysis of pure glycosides in concentrations from 2 to 10%.
J, NAGHSKI, C F, KREWSON
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Antioxidant Properties of Quercetin

2011
Quercetin, a plant-derived aglycone form of flavonoid glycosides, has been used as a nutritional supplement and may be beneficial against a variety of diseases, including cancer. We examined the antioxidant properties of quercetin. The reduction potential of quercetin was measured at various pH values using voltammetric methods, and its total ...
Mei, Zhang   +16 more
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Molecular imaging of the biological effects of quercetin and quercetin-rich foods

Mechanisms of Ageing and Development, 2004
The human diet contains several thousands of organic plant molecules (i.e. phytochemicals), many of which have significant bioactivities. The specific physiological effects of these compounds are impossible to predict from in vitro studies using cell cultures and cell-free model systems. Nutrigenomics, which may be defined as the application of genomic
Jan Øivind, Moskaug   +3 more
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Quercetin

2021
Fatma Tugce Guragac Dereli, Tarun Belwal
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Concentration and effect of quercetin.

Experimental hematology, 1996
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Larocca LM   +4 more
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Quercetin

Zeitschrift für Orthomolekulare Medizin, 2011
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