Results 51 to 60 of about 128,103 (312)

Negligible Effect of Quercetin in the Pharmacokinetics of Sulfasalazine in Rats and Beagles: Metabolic Inactivation of the Interaction Potential of Quercetin with BCRP

Pharmaceutics, 2021
Breast cancer resistance protein (BCRP) mediates pharmacokinetic drug interactions. This study evaluated the potential of quercetin to inhibit and induce BCRP in vitro and in vivo. The inhibition of BCRP was investigated for quercetin and its metabolites
Ju-Hee Oh, Dokeun Kim, Haejun Lee, Gyeonghee Kim, Taehoon Park, Min Chang Kim, Young-Joo Lee   +6 more
doaj   +1 more source

Effect of quercetin on adhesion and cell division of metastatic uveal melanoma cells

, 2023
This thesis aimed to review the effects of quercetin on the adhesion and cell division of metastatic uveal melanoma cells. Uveal melanoma (UM) is a rare but lethal type of cancer which affects the uvea of the eye.
Akegbesola, Adenike
core  

Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies

Advanced Engineering Materials, EarlyView.
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo, Daniela Winsley Valereto Friozi, Vinícius de Oliveira, Marcia Cristina Branciforti   +3 more
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Adaptable Covalent Organic Framework‐Hydrogel Microneedles for Glucose‐Responsive Isoliquiritigenin Delivery in Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou, Zongjie Hu, Xiuwen Li, Huaman Geng, Yang Liu, Yajie Wang, Yunshu Yang, Guangdong Zhou, Yujie Hua, Di Wang   +9 more
wiley   +1 more source

Preparation and Characterization of Quercetin Phospholipid Complex and Its Effect on the Oxidative Stability of Walnut Oil

Shipin gongye ke-ji
To expand the application of quercetin, quercetin phospholipid complexes were optimally prepared by the solvent method. The complexes were structurally characterized and evaluated for their antioxidant capacity in vitro, and the effect of the complexes ...
Yan XIANG, Yihan DU, Qiang HE, Qun SUN, Yi DONG, Zhongfeng TANG   +5 more
doaj   +1 more source

Suppression of Intracellular Reactive Oxygen Species in Human Corneal Epithelial Cells via the Combination of Quercetin Nanoparticles and Epigallocatechin Gallate and In Situ Thermosensitive Gel Formulation for Ocular Drug Delivery

Pharmaceuticals, 2021
Oxidative stress can cause several severe ophthalmological diseases. In this study, we developed a thermosensitive gel as a delivery system for two antioxidant substances, namely, quercetin and epigallocatechin gallate.
Chuda Chittasupho, Taepin Junmahasathien, Jiratchaya Chalermmongkol, Raksakul Wongjirasakul, Phuriwat Leesawat, Siriporn Okonogi   +5 more
doaj   +1 more source

Quercetin inhibits collagen-stimulated platelet activation through inhibition of multiple components of the glycoprotein VI signaling pathway

, 2003
Background: The regulation of platelet function by pharmacological agents that modulate platelet signaling haspharmacolo proven a successful approach to the prevention of thrombosis.
Cicmil, M, Jordan, P.A., Sage, T., C. M. Williams, G. P. Hubbard, T. Sage, Lovegrove, J.A., Stevens, J M; id_orcid, P. A. Jordan, J. M. Gibbins, Hubbard, G.P., M. Cicmil, Sage, T, Gibbins, J.M., Williams, C M, Williams, C.M., Gibbins, J M, Jordan, P A, Lovegrove, J A, Hubbard, G P, Stevens, J.M., J. A. Lovegrove, J. M. Stevens, Cicmil, M.   +23 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

The effect of quercetin on exercise induced cytokine response in trained cyclists [PDF]

, 2013
textQuercetin is a flavonoid found in commonly consumed fruits and vegetables that has exhibited powerful antioxidant and anti-inflammatory properties in rodents and in vitro.
Chou, Ting-Heng
core