Results 51 to 60 of about 57,525 (253)

Fabrication, Characterization, and In Vitro Testing of Quercetin–Copper(II) Complex

open access: yesNano Biomedicine and Engineering
Quercetin is a biologically active and widely used dietary flavonoid with robust antioxidant and chelating effects. However, due to its lesser solubility, it has poor bioavailability, which results in limited medicinal effects.
Sidra Sajid   +10 more
doaj   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

open access: yesAdvanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan   +5 more
wiley   +1 more source

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang   +11 more
wiley   +1 more source

Occurrence in food, metabolic rate and health benefits of quercetin

open access: yes, 2012
Quercetin, the most common member of the flavonoids family, is a group of chemical compounds that can be found in the plant kingdom. Fruits and vegetables - particularly citrus fruits, apples, onions, parsley, tea, and red wine - are the primary dietary ...
Villarán, María Carmen   +2 more
core   +1 more source

Preparation and Characterization of Quercetin Phospholipid Complex and Its Effect on the Oxidative Stability of Walnut Oil

open access: yesShipin gongye ke-ji
To expand the application of quercetin, quercetin phospholipid complexes were optimally prepared by the solvent method. The complexes were structurally characterized and evaluated for their antioxidant capacity in vitro, and the effect of the complexes ...
Yan XIANG   +5 more
doaj   +1 more source

Evaluation of the Mrp2-mediated flavonoid-drug interaction potential of quercetin in rats and in vitro models

open access: yesAsian Journal of Pharmaceutical Sciences, 2019
Quercetin is a biologically active flavonoid that has been used as a popular health supplement. It is reported that quercetin may cause flavonoid-drug interaction mediated by P-glycoprotein, the most predominant efflux transporter.
Ju-Hee Oh, Joo Hyun Lee, Young-Joo Lee
doaj   +1 more source

The effect of quercetin on exercise induced cytokine response in trained cyclists [PDF]

open access: yes, 2013
textQuercetin is a flavonoid found in commonly consumed fruits and vegetables that has exhibited powerful antioxidant and anti-inflammatory properties in rodents and in vitro.
Chou, Ting-Heng
core  

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

open access: yesAdvanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan   +7 more
wiley   +1 more source

Long‐Term Human Skin Platform for Modeling Chronic Inflammation, Environmental Stress, and Therapeutic Intervention

open access: yesAdvanced Science, EarlyView.
An advanced, long‐term human skin platform maintains native skin structure and key tissue functions for up to four weeks. The platform models chronic inflammation, aging‐related skin changes, and UVB damage, enabling drug and topical interventions—including anti‐inflammatory therapy, senolytic treatment, and sunscreen—to be evaluated in intact human ...
Purnendu Kumar Sharma   +14 more
wiley   +1 more source

Suppression of Intracellular Reactive Oxygen Species in Human Corneal Epithelial Cells via the Combination of Quercetin Nanoparticles and Epigallocatechin Gallate and In Situ Thermosensitive Gel Formulation for Ocular Drug Delivery

open access: yesPharmaceuticals, 2021
Oxidative stress can cause several severe ophthalmological diseases. In this study, we developed a thermosensitive gel as a delivery system for two antioxidant substances, namely, quercetin and epigallocatechin gallate.
Chuda Chittasupho   +5 more
doaj   +1 more source

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