Results 51 to 60 of about 141,999 (309)

Quercetin Suppresses Human Glioblastoma Migration and Invasion via GSK3β/β-catenin/ZEB1 Signaling Pathway

Frontiers in Pharmacology, 2022
High invasiveness is a biological and clinical characteristic of glioblastoma and predicts poor prognosis of patients. Quercetin, a natural flavonoid compound, exhibits anticancer activity.
Bo Chen, Bo Chen, Xiaoli Li, Xiaoli Li, Xiaoli Li, Lihong Wu, Lihong Wu, Duanfang Zhou, Duanfang Zhou, Yi Song, Yi Song, Limei Zhang, Limei Zhang, Qiuya Wu, Qiuya Wu, Qichen He, Qichen He, Gang Wang, Gang Wang, Xu Liu, Xu Liu, Hui Hu, Hui Hu, Hui Hu, Weiying Zhou, Weiying Zhou, Weiying Zhou   +26 more
doaj   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source

Effect of matter other than grapes on quercetin evolution and key wine parameters

IVES Technical Reviews
Quercetin instability is a practical concern in red wines because low-solubility quercetin aglycone can form haze or crystals during storage. This study evaluated whether sub-threshold levels of matter other than grapes (MOG; < 3 % w/v), as encountered ...
Shuyan Liu, Daniele Pizzinato, Celine Sparrow, Simone Vincenzi   +3 more
doaj   +1 more source

Negligible Effect of Quercetin in the Pharmacokinetics of Sulfasalazine in Rats and Beagles: Metabolic Inactivation of the Interaction Potential of Quercetin with BCRP

Pharmaceutics, 2021
Breast cancer resistance protein (BCRP) mediates pharmacokinetic drug interactions. This study evaluated the potential of quercetin to inhibit and induce BCRP in vitro and in vivo. The inhibition of BCRP was investigated for quercetin and its metabolites
Ju-Hee Oh, Dokeun Kim, Haejun Lee, Gyeonghee Kim, Taehoon Park, Min Chang Kim, Young-Joo Lee   +6 more
doaj   +1 more source

Smart Antibacterial Coatings: Harnessing Bacterial Redox Activity for Infection Control

Advanced Materials Interfaces, EarlyView.
In this study, we have shown that ceftazidime‐loaded poly(3,4‐ethylenedioxythiophene) (PEDOT@CAZ) functions as a smart, redox‐responsive antibacterial coating that couples bacterial electrical activity with localized antibiotic delivery. Shewanella oneidensis and Pseudomonas aeruginosa induced distinct redox responses in PEDOT, reflecting their ...
Abdullah, Szymon Smołka, Kamran Ayaz, Sara Shakibania, Sajida Maryam, Taral Patel, Roman Turczyn, Ewa Zabłocka‐Godlewska, Katarzyna Krukiewicz   +8 more
wiley   +1 more source

Quercetin suppresses cyclooxygenase-2 expression and angiogenesis through inactivation of P300 signaling.

PLoS ONE, 2011
Quercetin, a polyphenolic bioflavonoid, possesses multiple pharmacological actions including anti-inflammatory and antitumor properties. However, the precise action mechanisms of quercetin remain unclear.
Xiangsheng Xiao, Dingbo Shi, Liqun Liu, Jingshu Wang, Xiaoming Xie, Tiebang Kang, Wuguo Deng   +6 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Quercetin inhibits LPS-induced macrophage migration by suppressing the iNOS/FAK/paxillin pathway and modulating the cytoskeleton

Cell Adhesion & Migration, 2019
The natural flavonoid quercetin has antioxidant, anti-inflammatory, and anticancer effects. We investigated the effect of quercetin on lipopolysaccharide (LPS)-induced macrophage migration.
Shuna Cui, Qingqing Wu, Juan Wang, Min Li, Jing Qian, Shihua Li   +5 more
doaj   +1 more source

Protective and therapeutic effects of nanoliposomal quercetin on acute liver injury in rats

BMC Pharmacology and Toxicology, 2020
Background Quercetin, a pigment (flavonoid) found in many plants and foods, has good effects on protecting liver function but poor solubility and bioavailability in vivo.
Xiangyan Liu, Yang Zhang, Ling Liu, Yifeng Pan, Yu Hu, Pu Yang, Mingmei Liao   +6 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source