Results 51 to 60 of about 202,389 (329)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Normalized Storage Model Construction and Query Optimization of Book Multi-Source Heterogeneous Massive Data

open access: yesIEEE Access, 2023
According to the characteristics of massive, multi-source, heterogeneous, and rapid growth of book literature data information from the perspective of the metaverse, in order to meet the requirements of efficient management and rapid retrieval such as ...
Dailin Wang, Lina Liu, Yali Liu
doaj   +1 more source

Deep Query Optimization [PDF]

open access: yesProceedings of the 2019 International Conference on Management of Data, 2019
In recent decades, we observed the rapid growth of several big data platforms. Each of them is designed for specific demands. For instance, Spark can efficiently process iterative queries, while Storm is designed for in-memory processing. In this context, the complexity of these distributed systems make it much harder to develop rigorous cost models ...
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Cardinality Estimator in Complex Database Systems Based on TreeLSTM

open access: yesSensors, 2023
Cardinality estimation is critical for database management systems (DBMSs) to execute query optimization tasks, which can guide the query optimizer in choosing the best execution plan.
Kaiyang Qi, Jiong Yu, Zhenzhen He
doaj   +1 more source

Sampling-Based Query Re-Optimization

open access: yes, 2016
Despite of decades of work, query optimizers still make mistakes on "difficult" queries because of bad cardinality estimates, often due to the interaction of multiple predicates and correlations in the data.
Bruno N.   +5 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Minimization of data base query's conditions: evoluation of efficiency

open access: yesТруды Института системного программирования РАН, 2018
This paper describes enhanced algorisms of query lexical optimization. These algorisms detect and remove redundant conditions from query restriction to simplify it.
N. A. Mendkovich, S. D. Kuznetsov
doaj  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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