Results 51 to 60 of about 193,669 (327)
Consistent and Flexible Selectivity Estimation for High-dimensional Data
, 2020 Selectivity estimation aims at estimating the number of database objects that satisfy a selection criterion. Answering this problem accurately and efficiently is essential to many applications, such as density estimation, outlier detection, query ...
Ishikawa, Yoshiharu +7 more
core +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Ontological queries: Rewriting and optimization
2011 IEEE 27th International Conference on Data Engineering, 2011 Ontological queries are evaluated against an enterprise ontology rather than directly on a database. The evaluation and optimization of such queries is an intriguing new problem for database research. In this paper we discuss two important aspects of this problem: query rewriting and query optimization. Query rewriting consists of the compilation of an
Georg Gottlob +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A Cardinality Estimator in Complex Database Systems Based on TreeLSTM
Sensors, 2023 Cardinality estimation is critical for database management systems (DBMSs) to execute query optimization tasks, which can guide the query optimizer in choosing the best execution plan.
Kaiyang Qi, Jiong Yu, Zhenzhen He
doaj +1 more source
Sampling-Based Query Re-Optimization
, 2016 Despite of decades of work, query optimizers still make mistakes on "difficult" queries because of bad cardinality estimates, often due to the interaction of multiple predicates and correlations in the data.
Bruno N. +5 more
core +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Minimization of data base query's conditions: evoluation of efficiency
Труды Института системного программирования РАН, 2018 This paper describes enhanced algorisms of query lexical optimization. These algorisms detect and remove redundant conditions from query restriction to simplify it.
N. A. Mendkovich, S. D. Kuznetsov
doaj
Query Optimization in Distributed Database Based on Improved Artificial Bee Colony Algorithm
Applied SciencesQuery optimization is one of the key factors affecting the performance of database systems that aim to enact the query execution plan with minimum cost. Particularly in distributed database systems, due to the multiple copies of the data that are stored ...
Yan Du, Zhi Cai, Zhiming Ding
doaj +1 more source