Results 71 to 80 of about 34,853 (265)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Multi-Query Optimization Revisited: A Full-Query Algebraic Method. [PDF]

open access: yesProc IEEE Int Conf Big Data, 2022
Tu Y, Eslami M, Xu Z, Charkhgard H.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Ontological queries: Rewriting and optimization

open access: yes2011 IEEE 27th International Conference on Data Engineering, 2011
Ontological queries are evaluated against an enterprise ontology rather than directly on a database. The evaluation and optimization of such queries is an intriguing new problem for database research. In this paper we discuss two important aspects of this problem: query rewriting and query optimization. Query rewriting consists of the compilation of an
Georg Gottlob   +2 more
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Cache Pattern with Multi-Queries

open access: yesAdvances in Electrical and Computer Engineering, 2010
This article proposes a cache pattern with multi-queries and describes the multi-query optimization with scheduling, caching and pipelining. A set of cache patterns is derived from a set of class of multi-queries that are loaded into the cache.
TUDOR, N. L.
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Left-deep join order selection with higher-order unconstrained binary optimization on quantum computers

open access: yesFrontiers in Computer Science
Join order optimization is among the most crucial query optimization problems, and its central position is also evident in the new research field where quantum computing is applied to database optimization and data management.
Valter Uotila
doaj   +1 more source

One Size Does Not Fit All: Querying Web Polystores

open access: yesIEEE Access, 2019
Data retrieval systems are facing a paradigm shift due to the proliferation of specialized data storage engines (SQL, NoSQL, Column Stores, MapReduce, Data Stream, and Graph) supported by varied data models (CSV, JSON, RDB, RDF, and XML).
Yasar Khan   +5 more
doaj   +1 more source

Optimizing navigational graph queries

open access: yesThe VLDB Journal
Abstract We study the optimization of navigational graph queries in the form of the Regular Queries, i.e., queries which combine recursive and pattern-matching fragments. Current approaches to their evaluation are not effective in practice.
Thomas Mulder   +2 more
openaire   +3 more sources

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