Results 61 to 70 of about 193,669 (327)
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
SMOQE: A System for Providing Secure Access to XML [PDF]
, 2006 XML views have been widely used to enforce access control, support data integration, and speed up query answering. In many applications, e.g., XML security enforcement, it is prohibitively expensive to materialize and maintain a large number of views ...
Fan, Wenfei +3 more
core +1 more source
Optimization of distributed tree queries
Journal of Computer and System Sciences, 1984 In this paper the problem of finding an optimum strategy of semi-joins for solving tree queries is studied under the objective of total time minimization. Tree queries that are conjunctions of equi-join clauses such that any two relations in the query have at most one attribute in common are considered.
Clement Yu +2 more
openaire +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
New algorithms for query modifications
Моделирование и анализ информационных систем, 2009 New algorithms for query modifications are proposed. These algorithms involve the lexical optimization based on the mathematical transformations that have never been used for the query optimization before.
S. D. Kuznetsov, N. A. Mendkovich
doaj
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
SQL UŽKLAUSŲ OPTIMIZAVIMO TYRIMAS = SQL QUERY OPTIMIZATION RESEARCH
Taikomieji tyrimai studijose ir praktikoje, 2017 Although scientific literature studies different aspects of SQL query optimization the major part of researches is limited to the theoretical analysis of problems.
Jurgita Lieponienė
doaj
A Novel Urban Emergency Path Planning Method Based on Vector Grid Map
IEEE Access, 2020 When an emergency occurs in the city, a large area of road congestion usually occurs. Therefore, it is particularly important to provide an effective emergency path planning strategy for vehicles.
Bowen Yang +5 more
doaj +1 more source
Query optimization for dynamic imputation [PDF]
Proceedings of the VLDB Endowment, 2017 Missing values are common in data analysis and present a usability challenge. Users are forced to pick between removing tuples with missing values or creating a cleaned version of their data by applying a relatively expensive imputation strategy. Our system, ImputeDB, incorporates imputation into a cost-based query optimizer, performing necessary ...
Cambronero, José +3 more
openaire +3 more sources