Results 61 to 70 of about 4,465,122 (351)
Efficient and Provable Multi-Query Optimization
, 2017 Complex queries for massive data analysis jobs have become increasingly commonplace. Many such queries contain com- mon subexpressions, either within a single query or among multiple queries submitted as a batch.
Kathuria, Tarun, Sudarshan, S.
core +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Relational Approach to Logical Query Optimization of XPath [PDF]
, 2004 To be able to handle the ever growing volumes of XML documents, effective and efficient data management solutions are needed. Managing XML data in a relational DBMS has great potential.
Keulen, Maurice van
core +1 more source
Query-guided End-to-End Person Search
, 2019 Person search has recently gained attention as the novel task of finding a person, provided as a cropped sample, from a gallery of non-cropped images, whereby several other people are also visible. We believe that i.
Amin, Sikandar +3 more
core +1 more source
Query Rewriting and Optimization for Ontological Databases [PDF]
TODS, 2014 Ontological queries are evaluated against a knowledge base consisting of an extensional database and an ontology (i.e., a set of logical assertions and constraints that derive new intensional knowledge from the extensional database), rather than directly
G. Gottlob, G. Orsi, Andreas Pieris
semanticscholar +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Query Complexity of Derivative-Free Optimization [PDF]
, 2012 This paper provides lower bounds on the convergence rate of Derivative Free Optimization (DFO) with noisy function evaluations, exposing a fundamental and unavoidable gap between the performance of algorithms with access to gradients and those with ...
Jamieson, Kevin G. +2 more
core +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source