Results 71 to 80 of about 198,739 (283)

Query Complexity of Derivative-Free Optimization [PDF]

open access: yes, 2012
This paper provides lower bounds on the convergence rate of Derivative Free Optimization (DFO) with noisy function evaluations, exposing a fundamental and unavoidable gap between the performance of algorithms with access to gradients and those with ...
Jamieson, Kevin G.   +2 more
core   +1 more source

Convex Optimization for Linear Query Processing under Approximate Differential Privacy

open access: yes, 2016
Differential privacy enables organizations to collect accurate aggregates over sensitive data with strong, rigorous guarantees on individuals' privacy. Previous work has found that under differential privacy, computing multiple correlated aggregates as a
Hao, Zhifeng   +3 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

A Novel Urban Emergency Path Planning Method Based on Vector Grid Map

open access: yesIEEE Access, 2020
When an emergency occurs in the city, a large area of road congestion usually occurs. Therefore, it is particularly important to provide an effective emergency path planning strategy for vehicles.
Bowen Yang   +5 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

An extension of SPARQL for expressing qualitative preferences

open access: yes, 2017
In this paper we present SPREFQL, an extension of the SPARQL language that allows appending a PREFER clause that expresses "soft" preferences over the query results obtained by the main body of the query.
C Domshlak   +12 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Learning Tuple Probabilities [PDF]

open access: yes, 2016
Learning the parameters of complex probabilistic-relational models from labeled training data is a standard technique in machine learning, which has been intensively studied in the subfield of Statistical Relational Learning (SRL), but---so far---this is
Dylla, Maximilian, Theobald, Martin
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Optimization of Queries Containing Conjunctions of Conditions

open access: yesМоделирование и анализ информационных систем, 2011
A new algorithm for query optimization is proposed. This algorithm simplifies queries restriction containing multi-attribute conditions. It also solves the problem of "Condition AND Conjunction of conditions" expressions.
S. D. Kuznetsov, N. A. Mendkovich
doaj  

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