Results 81 to 90 of about 4,667,593 (375)

Clinical significance of stratifying prostate cancer patients through specific circulating genes

open access: yesMolecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian   +12 more
wiley   +1 more source

Query Complexity of Derivative-Free Optimization [PDF]

open access: yes, 2012
This paper provides lower bounds on the convergence rate of Derivative Free Optimization (DFO) with noisy function evaluations, exposing a fundamental and unavoidable gap between the performance of algorithms with access to gradients and those with ...
Jamieson, Kevin G.   +2 more
core   +1 more source

Query-guided End-to-End Person Search

open access: yes, 2019
Person search has recently gained attention as the novel task of finding a person, provided as a cropped sample, from a gallery of non-cropped images, whereby several other people are also visible. We believe that i.
Amin, Sikandar   +3 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Minimization of data base query's conditions: evoluation of efficiency

open access: yesТруды Института системного программирования РАН, 2018
This paper describes enhanced algorisms of query lexical optimization. These algorisms detect and remove redundant conditions from query restriction to simplify it.
N. A. Mendkovich, S. D. Kuznetsov
doaj  

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

open access: yesMolecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger   +2 more
wiley   +1 more source

Investigation of the Uniformity of Gel Shrinkage by Imaging Tracer Particles Using X‐Ray Microtomography

open access: yesAdvanced Engineering Materials, EarlyView., 2023
A novel method for tracking structural changes in gels using widely accessible microcomputed tomography is presented and validated for various hydro‐, alco‐, and aerogels. The core idea of the method is to track positions of micrometer‐sized tracer particles entrapped in the gel and relate them to the density of the gel network.
Anja Hajnal   +3 more
wiley   +1 more source

Query Optimization in Distributed Database Based on Improved Artificial Bee Colony Algorithm

open access: yesApplied Sciences
Query optimization is one of the key factors affecting the performance of database systems that aim to enact the query execution plan with minimum cost. Particularly in distributed database systems, due to the multiple copies of the data that are stored ...
Yan Du, Zhi Cai, Zhiming Ding
doaj   +1 more source

Performance Evaluation of Query Plan Recommendation with Apache Hadoop and Apache Spark

open access: yesMathematics, 2022
Access plan recommendation is a query optimization approach that executes new queries using prior created query execution plans (QEPs). The query optimizer divides the query space into clusters in the mentioned method.
Elham Azhir   +3 more
doaj   +1 more source

An extension of SPARQL for expressing qualitative preferences

open access: yes, 2017
In this paper we present SPREFQL, an extension of the SPARQL language that allows appending a PREFER clause that expresses "soft" preferences over the query results obtained by the main body of the query.
C Domshlak   +12 more
core   +1 more source

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